Ohtsuka Takashi, Nomori Hiroaki, Watanabe Kenichi, Naruke Tsuguo
Department of Thoracic Surgery, Saiseikai Central Hospital.
Nihon Kokyuki Gakkai Zasshi. 2005 Feb;43(2):99-102.
Benign metastasizing leiomyoma (BML) is the term used to describe multiple benign pulmonary leiomyomatous lesions occurring in patients with a previous history of uterine leiomyoma. On the other hand, pulmonary fibroleiomyomatous hamartoma (FLH) is also multiple nodules and the discrimination of the nodules between BML and FLH is not determined. We report the case of 36-year-old woman who had a previous history of uterine leiomyoma. The woman was referred to our hospital for evaluation of asymptomatic bilateral nodules in chest roentgenogram examination. A chest X-ray showed multiple nodules in bilateral lung. Chest computed tomography (CT) scan showed round nodules well-defined margins in bilateral lung. Thoracoscopic partial resection of the lung was performed. Pathological examination revealed that the tumor composed of spindle-shaped smooth muscle cells and its characteristics were remarkably similar to those of the previously resected uterine leiomyoma. Therefore, these lung tumors could be considered to be lung metastases from a uterine leiomyoma (benign metastasizing leiomyoma).
良性转移性平滑肌瘤(BML)是用于描述既往有子宫平滑肌瘤病史的患者出现的多发性良性肺平滑肌瘤性病变的术语。另一方面,肺纤维平滑肌瘤性错构瘤(FLH)也是多发性结节,BML与FLH结节之间的鉴别尚未明确。我们报告了一例36岁有子宫平滑肌瘤病史的女性病例。该女性因胸部X线检查发现无症状双侧结节而转诊至我院。胸部X线显示双侧肺有多个结节。胸部计算机断层扫描(CT)显示双侧肺内边界清晰的圆形结节。进行了胸腔镜肺部分切除术。病理检查显示肿瘤由梭形平滑肌细胞组成,其特征与先前切除的子宫平滑肌瘤显著相似。因此,这些肺肿瘤可被认为是子宫平滑肌瘤的肺转移(良性转移性平滑肌瘤)。