Jain Samit S, Somani Piyush O, Mahey Rajeshkumar C, Shah Dharmesh K, Contractor Qais Q, Rathi Pravin M
Samit S Jain, Piyush O Somani, Dharmesh K Shah, Qais Q Contractor, Pravin M Rathi, Department of Gastroenterology, Bai Yamunabai Laxman Nair Hospital, Topiwala National Medical College, Mumbai 400008, India.
World J Gastrointest Endosc. 2013 Nov 16;5(11):581-3. doi: 10.4253/wjge.v5.i11.581.
Esophageal tuberculosis is rare, constituting about 0.3% of gastrointestinal tuberculosis. It presents commonly with dysphagia, cough, chest pain in addition to fever and weight loss. Complications may include hemorrhage from the lesion, development of arterioesophageal fistula, esophagocutaneous fistula or tracheoesophageal fistula. There are very few reports of esophageal tuberculosis presenting with hematemesis due to ulceration. We report a patient with hematemesis that was due to the erosion of tuberculous subcarinal lymph nodes into the esophagus. A 15-year-old boy presented with hemetemesis as his only complaint. Esophagogastroduodenoscopy (EGD) revealed an eccentric ulcerative lesion involving 50% of circumference of the esophagus. Biopsy showed caseating epitheloid granulomas with lymphocytic infiltrates suggestive of tuberculosis. Computerised tomography of the thorax revealed thickening of the mid-esophagus with enlarged mediastinal lymph nodes in the subcarinal region compressing the esophagus along with moderate right sided pleural effusion. Patient was treated with anti-tuberculosis therapy (Rifampicin, Isoniazid, Pyrazinamide, Ethambutol) for 6 mo. Repeat EGD showed scarring and mucosal tags with complete resolution of the esophageal ulcer.
食管结核较为罕见,约占胃肠道结核的0.3%。其常见症状除发热和体重减轻外,还包括吞咽困难、咳嗽及胸痛。并发症可能包括病变部位出血、形成食管动脉瘘、食管皮肤瘘或气管食管瘘。因溃疡导致呕血的食管结核报道极少。我们报告1例因结核性隆突下淋巴结侵蚀食管导致呕血的患者。一名15岁男孩仅以呕血为主诉就诊。食管胃十二指肠镜检查(EGD)显示一个偏心性溃疡性病变,累及食管周长的50%。活检显示干酪样上皮样肉芽肿伴淋巴细胞浸润,提示为结核。胸部计算机断层扫描显示食管中段增厚,隆突下区域纵隔淋巴结肿大压迫食管,同时伴有中度右侧胸腔积液。患者接受抗结核治疗(利福平、异烟肼、吡嗪酰胺、乙胺丁醇)6个月。复查EGD显示瘢痕形成及黏膜垂片,食管溃疡完全愈合。