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食管鳞状细胞癌和小细胞癌罕见合并肿瘤并伴有单独淋巴结转移:一例报告。

A rare collision tumor of squamous carcinoma and small cell carcinoma in esophagus involved with separate lymph nodes: a case report.

机构信息

Department of Thoracic Surgery, Zhongshan Hospital of Fudan University, Shanghai 200032, China.

出版信息

J Thorac Dis. 2013 Oct;5(5):E203-6. doi: 10.3978/j.issn.2072-1439.2013.09.13.

DOI:10.3978/j.issn.2072-1439.2013.09.13
PMID:24255793
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3815725/
Abstract

We report a case of an esophageal collision tumor composed of squamous cell carcinoma and small cell carcinoma (SmCC). A 66-year-old man complained of chest pain after oral intake for nearly one month. The patient received two cycles of neoadjuvant platinum-based combination chemotherapy and enhanced computed tomography showed a partial response of the tumor. He then underwent a thoracolaparoscopic esophagectomy with extensive mediastinal lymphadenectomy. Two cycles of chemotherapy and prophylactic irradiation of the lymphatic drainage region were sequentially achieved after surgery. The patient has survived for more than 18 months with no evidence of recurrent disease since surgical resection.

摘要

我们报告一例食管碰撞瘤,由鳞状细胞癌和小细胞癌(SmCC)组成。一名 66 岁男性在近一个月的口服摄入后抱怨胸痛。患者接受了两个周期的新辅助铂类联合化疗,增强计算机断层扫描显示肿瘤部分缓解。然后他接受了胸腹腔镜食管切除术和广泛的纵隔淋巴结清扫术。手术后,他先后进行了两个周期的化疗和淋巴引流区域的预防性放疗。自手术切除以来,患者已存活超过 18 个月,无疾病复发迹象。

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本文引用的文献

1
Long-term survival of advanced small cell carcinoma of the esophagus after resection: a case report.食管小细胞癌术后长期生存一例报告。
Anticancer Res. 2013 Feb;33(2):595-600.
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Collision tumor of the mediastinum: a rare entity.纵隔碰撞瘤:一种罕见的实体。
Ann Thorac Surg. 2013 Jan;95(1):330-2. doi: 10.1016/j.athoracsur.2012.06.030. Epub 2012 Dec 25.
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Extensive mediastinal lymphadenectomy during minimally invasive esophagectomy: optimal results from a single center.微创食管切除术期间广泛的纵隔淋巴结清扫术:单中心的最佳结果。
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Global cancer statistics.全球癌症统计数据。
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Non-operative management of small cell carcinoma of esophagus.食管小细胞癌的非手术治疗
Dis Esophagus. 2007;20(6):487-90. doi: 10.1111/j.1442-2050.2007.00635.x.
7
Effective treatment with chemotherapy and surgery for advanced small cell carcinoma of the esophagus.化疗与手术对晚期食管小细胞癌的有效治疗。
Hepatogastroenterology. 2004 Jul-Aug;51(58):1027-9.
8
Surgery for unusual histopathologic variants of esophageal neoplasms: a report of 23 cases with emphasis on histopathologic characteristics.食管肿瘤罕见组织病理学变异型的手术治疗:23例报告并着重分析组织病理学特征
Ann Surg Oncol. 2003 Apr;10(3):261-7. doi: 10.1245/aso.2003.05.029.
9
Case report: esophageal collision tumor (oat cell carcinoma and adenocarcinoma) in Barrett's esophagus: immunohistochemical, electron microscopy and LOH analysis.病例报告:巴雷特食管中的食管碰撞瘤(燕麦细胞癌和腺癌):免疫组织化学、电子显微镜及杂合性缺失分析
Histol Histopathol. 2003 Jan;18(1):1-5. doi: 10.14670/HH-18.1.
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Dis Esophagus. 2002;15(3):237-41. doi: 10.1046/j.1442-2050.2002.00244.x.