过量饲喂精氨酸对肉鸡脂肪生成基因表达及生长性能的影响。

The effect of feeding excess arginine on lipogenic gene expression and growth performance in broilers.

Ebrahimi M, Zare Shahneh A, Shivazad M, Ansari Pirsaraei Z, Tebianian M, Ruiz-Feria C A, Adibmoradi M, Nourijelyani K, Mohamadnejad F

a Faculty of Agricultural Science , University of Tabriz , Tabriz , Iran.

Br Poult Sci. 2014 Feb;55(1):81-8. doi: 10.1080/00071668.2013.864381.

Abstract

Reducing excess fat accretion is important for both human health and animal production. The present study was conducted to investigate the effects of arginine (Arg) on the regulation of lipogenic gene expression and on growth performance. 2. One-d-old female broiler chicks (Ross, n = 192) were used in a completely randomised design with 4 dietary treatments in which diets included 100% (CTL), 153% (LArg), 168% (MArg) and 183% (HArg) of the recommended concentration of digestible Arg. 3. Results showed that high concentrations of Arg improved body weight gain, feed efficiency, meat production, fat and crude protein content of breast muscle and plasma thyroid hormones. Conversely, abdominal fat, cholesterol, triglyceride and urea were lower with higher concentrations of Arg. Dietary arginine increased lipogenic gene expression in muscles, while decreasing those in adipose tissue and liver. 4. It was concluded that increasing Arg in the diet reduced abdominal fat content, enhanced intramuscular fat and increased muscle and protein gain. Furthermore, Arg supplementation at the MArg concentration improved growth performance, and at HArg had the greatest effect on fat reduction.

摘要

减少过多的脂肪堆积对人类健康和动物生产都很重要。本研究旨在探讨精氨酸（Arg）对脂肪生成基因表达调控及生长性能的影响。2. 选用1日龄雌性肉仔鸡（罗斯品种，n = 192），采用完全随机设计，设4种日粮处理，日粮中可消化精氨酸含量分别为推荐浓度的100%（CTL）、153%（LArg）、168%（MArg）和183%（HArg）。3. 结果表明，高浓度精氨酸可提高体重增加、饲料效率、产肉量、胸肌脂肪和粗蛋白含量以及血浆甲状腺激素水平。相反，高浓度精氨酸可降低腹脂、胆固醇、甘油三酯和尿素水平。日粮精氨酸增加了肌肉中脂肪生成基因的表达，同时降低了脂肪组织和肝脏中的表达。4. 得出的结论是，日粮中增加精氨酸可降低腹脂含量，增加肌内脂肪，增加肌肉和蛋白质的增加量。此外，添加MArg浓度的精氨酸可改善生长性能，添加HArg浓度的精氨酸对减脂效果最佳。