Department of Chemistry at Portland State University, PO Box 751, Portland, Oregon 97207, USA.
Nat Chem. 2013 Dec;5(12):987-9. doi: 10.1038/nchem.1811.
An RNA replicase ribozyme has long been sought by chemists interested in the origin of life. Now, a selection strategy employing a low-temperature water–ice mixture as the medium has led to discovery of a ribozyme that can catalyse polymerization of an RNA chain greater than its own length.
化学家们一直致力于寻找与生命起源有关的 RNA 复制酶核酶。现在,一种采用低温水-冰混合物作为介质的选择策略导致了一种核酶的发现,该核酶能够催化大于自身长度的 RNA 链的聚合。