Tsitouridis I, Papaioannou S, Arvaniti M, Tsitouridis K, Rodokalakis G, Papastergiou C
Radiology Department Papageorgiou General Hospital; Thessaloniki, Greece -
Neuroradiol J. 2009 Jan 20;21(6):773-9. doi: 10.1177/197140090802100604.
Virchow-Robin spaces are enclosed spaces filled with interstitial fluid and covered with pia that accompany arteries, arterioles, veins and venules as they perforate the brain. They are round, linear or punctuate areas depending on the image that parallel cerebrospinal fluid attenuation or signal intensity. They are classically described as isointense to cerebrospinal fluid on images obtained with all pulse sequences. They appear hypointense relative to brain on T1-weighted MR scans and present a high signal intensity on T2-weighted MR scans. They also show complete signal suppression on fluid-attenuated inversion recovery (FLAIR) scans and no enhancement after intravenous contrast administration. However, many pathologic states result in abnormal dilation with an increased number of Virchow-Robin spaces visible on MRI imaging and many pathological conditions cause the spaces to enhance. The purpose of this study is to present the major causes of Virchow-Robin enhancement.
血管周围间隙是充满间质液并被软脑膜覆盖的封闭间隙，当动脉、小动脉、静脉和小静脉穿透脑实质时，这些间隙伴随它们走行。根据影像表现，它们呈圆形、线性或点状区域，其信号与脑脊液衰减或信号强度相似。传统上，在所有脉冲序列获得的图像上，它们被描述为与脑脊液等信号。在T1加权磁共振扫描上，它们相对于脑呈低信号，而在T2加权磁共振扫描上呈高信号强度。在液体衰减反转恢复（FLAIR）扫描上它们也表现为完全信号抑制，静脉注射造影剂后无强化。然而，许多病理状态会导致血管周围间隙异常扩张，在MRI成像上可见数量增多，并且许多病理状况会导致这些间隙出现强化。本研究的目的是阐述血管周围间隙强化的主要原因。
