Department of Gynecology, Universitair Ziekenhuis, Vrije Universiteit Brussel, Brussels, Belgium.
Department of Mechanical Engineering, Katholieke Universiteit Leuven, Heverlee, Belgium.
Int J Gynaecol Obstet. 2014 Feb;124(2):128-33. doi: 10.1016/j.ijgo.2013.07.031. Epub 2013 Oct 25.
To compare fetal and infant mortality between immigrant and native-born mothers in Flanders, Belgium.
In a population-based study, data from 326 166 neonatal deliveries, collected by the Study Center for Perinatal Epidemiology and the Belgian Civil Birth Registration system between January 2004 and December 2008, were analyzed. Immigrant mothers were defined as women born in any country other than Belgium, and were grouped by country of origin according to the World Bank Atlas definition of low-, middle-, and high-income countries. Odds ratios (ORs) and 95% confidence intervals (CIs) were estimated to evaluate the association between immigration and fetal/infant outcome.
In univariate analysis, fetal and infant mortality rates were significantly higher among immigrants than among native-born mothers (fetal: crude OR, 1.50; 95% CI, 1.29-1.75; infant: crude OR, 1.47; 95% CI, 1.29-1.67). Fetal/infant death rates were highest among mothers originating from low-income countries. In multivariate analysis, however, most differences became non-significant: only the early neonatal death rate remained significantly higher (adjusted OR, 1.30; 95% CI, 1.06-1.60), whereas the fetal death rate appeared lower (adjusted OR, 0.67; 95% CI, 0.57-0.80), among immigrant mothers.
After adjustment for relevant characteristics, fetal/infant mortality was comparable between immigrant women and native-born women in Flanders.
比较比利时佛兰德斯地区移民和本地出生母亲的胎儿和婴儿死亡率。
在一项基于人群的研究中,分析了 2004 年 1 月至 2008 年 12 月期间,由围产流行病学研究中心和比利时民事出生登记系统收集的 326166 例新生儿分娩数据。移民母亲被定义为出生于比利时以外任何国家的女性,并根据世界银行地图集的定义,按原籍国分为低收入、中等收入和高收入国家。使用比值比(ORs)和 95%置信区间(CIs)来评估移民与胎儿/婴儿结局之间的关联。
在单因素分析中,移民母亲的胎儿和婴儿死亡率明显高于本地出生母亲(胎儿:粗 OR,1.50;95%CI,1.29-1.75;婴儿:粗 OR,1.47;95%CI,1.29-1.67)。来自低收入国家的母亲的胎儿/婴儿死亡率最高。然而,在多因素分析中,大多数差异变得不显著:只有早期新生儿死亡率仍然显著升高(调整后的 OR,1.30;95%CI,1.06-1.60),而胎儿死亡率似乎较低(调整后的 OR,0.67;95%CI,0.57-0.80),在移民母亲中。
在调整了相关特征后,佛兰德斯地区的移民妇女与本地出生妇女的胎儿/婴儿死亡率相当。