SPE: Study Centre for Perinatal Epidemiology, Brussels, Belgium.
Eur J Obstet Gynecol Reprod Biol. 2010 Jan;148(1):13-6. doi: 10.1016/j.ejogrb.2009.08.016.
To assess, in a homogenous population of primiparous women, how fetal and infant (=first year of life) mortality varied by the mothers' level of education.
We conducted an observational study in Flanders (Northern Belgium) involving 170,948 primiparous women who delivered in Flanders during the period 1999-2006, and their 174,495 babies. We linked the maternal education (3 levels) with a series of obstetrical and perinatal events, with special emphasis on fetal and infant death. A logistic regression analysis was performed to adjust for confounders.
The incidence of fetal (0.21% - high level of education; 0.35% - medium level; 0.84% - low level) and infant mortality (0.32%; 0.41%; 0.70%, respectively), followed an inverse maternal educational gradient: higher with a lower level of education. However, neonatal death (0-27 days) was independent of the educational level of the mother. The age of the woman at delivery, the use of assisted reproductive technology and the incidence of twin birth increased while the rates of preterm birth (7.7% - high level; 8.9% - medium level; 10% - low level) and low birth weight (7.2%; 9.5%; 11.8%, respectively) decreased with the mother's educational level.
Perinatal and obstetrical outcome differ according to the level of the education of the mother, which is a determinant of the incidence of fetal and post-neonatal death but not of early and late neonatal death (0-27 days).
在同质的初产妇人群中,评估母亲的受教育程度如何影响胎儿和婴儿(=生命的第一年)死亡率。
我们在佛兰德斯(比利时北部)进行了一项观察性研究,涉及 1999 年至 2006 年期间在佛兰德斯分娩的 170948 名初产妇及其 174495 名婴儿。我们将母亲的教育程度(3 个水平)与一系列产科和围产期事件联系起来,特别关注胎儿和婴儿死亡。进行了逻辑回归分析以调整混杂因素。
胎儿(0.21%-高教育水平;0.35%-中教育水平;0.84%-低教育水平)和婴儿死亡率(0.32%;0.41%;0.70%,分别)的发生率遵循母亲教育程度的逆梯度:教育程度越低,发生率越高。然而,新生儿死亡(0-27 天)与母亲的教育水平无关。产妇分娩时的年龄、辅助生殖技术的使用以及双胞胎出生的发生率增加,而早产率(7.7%-高教育水平;8.9%-中教育水平;10%-低教育水平)和低出生体重率(7.2%;9.5%;11.8%,分别)随着母亲的教育水平降低而降低。
围产期和产科结局因母亲的教育程度而异,这是胎儿和新生儿后死亡发生率的决定因素,但不是早期和晚期新生儿死亡(0-27 天)的决定因素。