从 Tabernaemontana divaricata 和 Tabernanthe iboga 的细胞悬浮培养物中分离得到的吲哚生物碱。
Indole alkaloids from cell suspension cultures of Tabernaemontana divaricata and Tabernanthe iboga.
机构信息
Institut für Pharmazeutische Biologie, Universität München, D-8000, München 2, FRG.
出版信息
Plant Cell Rep. 1983 Apr;2(2):105-7. doi: 10.1007/BF00270178.
From cell suspension cultures of Tabernaemontana divaricata and Tabernanthe iboga grown under standard conditions, six monoterpenoid indole alkaloids have been isolated and identified. T. divaricata synthesized apparicine, catharanthine, coronaridine, conoflorine, tubotaiwine and vinervine, whereas T. iboga produced tubotaiwine and conoflorine. Both cultures are a reasonable source for conoflorine, which is expected to be a good candidate for studying the mechanism of Aspidosperma type alkaloid formation at the cell-free level.
从标准条件下生长的 Tabernaemontana divaricata 和 Tabernanthe iboga 的细胞悬浮培养物中，分离并鉴定了六种单萜吲哚生物碱。T. divaricata 合成了阿朴菲碱、长春碱、冠狗牙花定碱、长春胺、土藤甲素和长春质碱，而 T. iboga 则产生了土藤甲素和长春胺。两种培养物都是阿朴菲碱的合理来源，阿朴菲碱有望成为在无细胞水平上研究 Aspidosperma 型生物碱形成机制的良好候选物。
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