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骨水泥增强骨质疏松性骨中的髋关节植入物:需要多少骨水泥以及应该放在哪里?

Cement augmentation of hip implants in osteoporotic bone: how much cement is needed and where should it go?

机构信息

AO Research Institute Davos, Davos, Switzerland; Department of Traumatology, University Hospitals Gasthuisberg, Leuven, Belgium; Department of Development and Regeneration, KU Leuven, Belgium.

出版信息

J Orthop Res. 2014 Mar;32(3):362-8. doi: 10.1002/jor.22522. Epub 2013 Nov 20.

Abstract

Several studies proved the beneficial effect of cement augmentation of proximal femoral nail antirotation (PFNA) blades on implant purchase in osteoporotic bone. We investigated the effect of different localizations and amounts of bone cement. Polyurethane foam specimens were instrumented with a PFNA blade and subsequently augmented with PMMA bone cement. Eight study groups were formed based on localization and amount of cement volume related to the blade. All specimens underwent cyclic loading with physiological orientation of the force vector until construct failure. Foam groups were compared between each other and to a cadaveric control group. The experiments revealed a significant dependency of implant purchase on localization and amount of cement. Biomechanically favorable cement positions were found at the implant tip and at the cranial side. However, none of the tested augmentation patterns performed significantly inferior to the cadaveric benchmark. These findings will allow surgeons to further reduce the amount of injected PMMA, decreasing the risk of cement leakage or cartilage damage.

摘要

多项研究证实了在骨质疏松性骨骼中,使用骨水泥增强股骨近端防旋髓内钉(PFNA)刀片对植入物的固定具有有益效果。我们研究了不同定位和骨水泥用量的影响。将聚氨酯泡沫标本用 PFNA 刀片进行处理,然后用 PMMA 骨水泥进行增强。根据与刀片相关的骨水泥体积的定位和数量,将标本分为八个研究组。所有标本均在生理力向量方向下进行循环加载,直至结构失效。将泡沫组相互之间以及与尸体对照组进行比较。实验表明,植入物的固定深度与骨水泥的定位和用量密切相关。在植入物尖端和颅侧发现了有利于生物力学的骨水泥位置。然而,没有一种测试的增强模式明显劣于尸体基准。这些发现将使外科医生能够进一步减少注射 PMMA 的量,降低骨水泥渗漏或软骨损伤的风险。

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