Murayama Y, Fukao K, Noguchi A, Takenaka O
J Med Primatol. 1986;15(3):215-26.
The cross-reactivity of peripheral blood mononuclear cells from 28 nonhuman primates was investigated with ten kinds of Leu series of monoclonal antibodies specific to human T-, natural killer/killer-, and B-cells. The chimpanzees possessed all ten epitopes examined but the orangutan lacked Leu4 and Leu7 epitopes and the gibbons lacked Leu4, Leu7, and Leu12 epitopes. In addition to the above epitopes, the Old World monkeys lacked Leu1 and Leu10 epitopes. The Leu3a/Leu2a cell ratios varied from 0 to 1.56 among the 12 macaque species and this enabled classification of these species into three groups. In the New World monkeys, Leu2a epitope was absent, whereas Leu11a epitope was detected in several species and Leu3a epitope was found only in the owl monkeys. The prosimians expressed only HLA-DR epitope.
用十种对人T细胞、自然杀伤/杀伤细胞和B细胞特异的Leu系列单克隆抗体，研究了28只非人灵长类动物外周血单个核细胞的交叉反应性。黑猩猩具有所检测的全部十个表位，但猩猩缺乏Leu4和Leu7表位，长臂猿缺乏Leu4、Leu7和Leu12表位。除上述表位外，旧大陆猴缺乏Leu1和Leu10表位。在12种猕猴中，Leu3a/Leu2a细胞比率在0到1.56之间变化，这使得这些物种能够被分为三组。在新大陆猴中，不存在Leu2a表位，而在几个物种中检测到Leu11a表位，并且仅在夜猴中发现Leu3a表位。原猴亚目动物仅表达HLA - DR表位。
