Kokame Gregg T
Division of Ophthalmology, Department of Surgery, University of Hawaii John A Burns School of Medicine, Honolulu, Hawaii; Retina Consultants of Hawaii, Honolulu, Hawaii, The Retina Center at Pali Momi, An Affiliation of Hawai'i Pacific Health, USA.
Open Ophthalmol J. 2013 Oct 31;7:82-4. doi: 10.2174/1874364101307010082. eCollection 2013.
This 47 year old female developed the new onset of a polypoidal subretinal neovascular membrane in the left eye 13 years after having polypoidal choroidal vasculopathy (PCV) treated in the right eye. The indocyanine green (ICG) angiography of the left eye at initial presentation showed a normal choroidal vascular pattern without PCV. The new development of a PCV complex on ICG angiography demonstrates that PCV is truly a type of subretinal neovascularization, and not a choroidal vascular abnormality. The optical coherence tomography shows that the polypoidal vascular complex lies above Bruch's membrane and beneath the retinal pigment epithelium, and not within the choroid. Treatment with high dose ranibizumab (2.0 mg) resulted in excellent polyp closure and regression of the branching vascular network. The documented new development of polypoidal subretinal vessels on ICG angiography and the response to ranibizumab supports that PCV is a polypoidal neovasculopathy (PNV).
这位47岁女性在右眼接受息肉样脉络膜血管病变（PCV）治疗13年后，左眼出现了新的息肉样视网膜下新生血管膜。初次就诊时左眼的吲哚菁绿（ICG）血管造影显示脉络膜血管形态正常，无PCV表现。ICG血管造影上新出现的PCV复合体表明，PCV确实是一种视网膜下新生血管形成类型，而非脉络膜血管异常。光学相干断层扫描显示，息肉样血管复合体位于布鲁赫膜上方和视网膜色素上皮下方，而非脉络膜内。高剂量雷珠单抗（2.0 mg）治疗导致息肉完全闭合，分支血管网消退。ICG血管造影记录的息肉样视网膜下血管新出现情况以及对雷珠单抗的反应支持PCV是一种息肉样新生血管病变（PNV）。
