Department of General Surgery, Chengdu Military General Hospital, Chengdu, Sichuan Province, P.R. China.
PLoS One. 2013 Nov 12;8(11):e78701. doi: 10.1371/journal.pone.0078701. eCollection 2013.
Urinary function can be protected following open lateral node dissection (LND) with pelvic autonomic nerve preservation (PANP) for advanced rectal cancer. However data regarding urinary function after laparoscopic LND with PANP have not been reported. The goal of this study was to determine the effects of laparoscopic LND with PANP on urinary function in male patients with rectal cancer.
Urine flowmetry was performed using an Urodyn flowmeter. Patients were also asked to complete the standardized International Prostate Symptom Score (IPSS) questionnaire before surgery and 6 months after. In total, this study consisted of 60 males with advanced rectal cancer.
No significant differences were seen in maximal urinary flow rate, voided volume or residual volume before and after surgery. The total IPSS score increased significantly after surgery and at least 41 patients (68.3%) reported there was no change in one of the seven IPSS questions.
Laparoscopic LND with PANP was relatively safe in preserving urinary function.
对于进展期直肠癌，行保留盆自主神经的开放性侧方淋巴结清扫术（LND）可保护其尿路功能。但目前尚无关于腹腔镜 LND 联合 PANP 对男性直肠癌患者尿路功能影响的报道。本研究旨在确定腹腔镜 LND 联合 PANP 对直肠癌男性患者尿路功能的影响。
采用尿流动力学仪进行尿流率测定。术前及术后 6 个月，患者还需完成标准化的国际前列腺症状评分（IPSS）问卷。本研究共纳入 60 例进展期直肠癌男性患者。
术前术后最大尿流率、排尿量及残余尿量比较，差异均无统计学意义。术后总 IPSS 评分显著升高，至少 41 例（68.3%）患者报告说，IPSS 的 7 个问题中至少有 1 个没有变化。
腹腔镜 LND 联合 PANP 对保护尿路功能相对安全。
