Department of Medicine, University of Washington Medical Center, 1959 Northeast Pacific Street, Box 356421, Seattle, WA 98195, USA.
Clin Geriatr Med. 2014 Feb;30(1):79-93. doi: 10.1016/j.cger.2013.10.008.
Clostridium difficile-associated illness is an increasingly prevalent and morbid condition. The elderly population is at a disproportionate risk of developing symptomatic disease and associated complications, including progression to severe or fulminant disease, and development of recurrent infections. This article analyzes the factors that influence C difficile disease propensity and severity, with particular attention directed toward features relevant to the rapidly aging population.
艰难梭菌相关性疾病是一种日益流行和严重的疾病。老年人发生有症状疾病和相关并发症(包括发展为严重或暴发性疾病,以及反复感染)的风险不成比例。本文分析了影响艰难梭菌疾病易感性和严重程度的因素,特别关注与快速老龄化人口相关的特征。