Fadok Valerie A
Dermatology Department, North Houston Veterinary Specialists, 1646 Spring Cypress Road #100, Spring, TX 77388, USA.
Vet Clin North Am Equine Pract. 2013 Dec;29(3):541-50. doi: 10.1016/j.cveq.2013.08.005. Epub 2013 Oct 25.
Horses develop many skin and respiratory disorders that have been attributed to allergy. These disorders include pruritic skin diseases, recurrent urticaria, allergic rhinoconjunctivitis, and reactive airway disease. Allergen-specific IgE has been detected in these horses, and allergen-specific immunotherapy is used to ameliorate clinical signs. The best understood atopic disease in horses is insect hypersensitivity, but the goal of effective treatment with allergen-specific immunotherapy remains elusive. In this review, updates in pathogenesis of allergic states and a brief mention of the new data on what is known in humans and dogs and how that relates to equine allergic disorders are discussed.
马匹会患上许多被认为与过敏有关的皮肤和呼吸道疾病。这些疾病包括瘙痒性皮肤病、复发性荨麻疹、过敏性鼻结膜炎和反应性气道疾病。在这些马匹中已检测到过敏原特异性IgE,并且使用过敏原特异性免疫疗法来改善临床症状。马匹中最被了解的特应性疾病是昆虫超敏反应,但通过过敏原特异性免疫疗法进行有效治疗的目标仍然难以实现。在这篇综述中,讨论了过敏状态发病机制的最新进展,并简要提及了关于人类和犬类已知情况的新数据以及这些数据与马类过敏性疾病的关系。