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将紧急医疗服务作为改善ST段抬高型心肌梗死系统治疗时间的一项策略。

Emergency medical services as a strategy for improving ST-elevation myocardial infarction system treatment times.

作者信息

Langabeer James R, Dellifraine Jami, Fowler Raymond, Jollis James G, Stuart Leilani, Segrest Wendy, Griffin Russell, Koenig William, Moyer Peter, Henry Timothy D

机构信息

Baylor College of Medicine, Houston, Texas.

University of Texas Health Sciences Center, Houston, Texas.

出版信息

J Emerg Med. 2014 Mar;46(3):355-62. doi: 10.1016/j.jemermed.2013.08.112. Epub 2013 Nov 22.

Abstract

BACKGROUND

Reducing delays in time to treatment is a key goal of ST-elevation myocardial infarction (STEMI) emergency care. Emergency medical services (EMS) are a critical component of the STEMI chain of survival.

STUDY OBJECTIVE

We sought to assess the impact of the careful integration of EMS as a strategy for improving systemic treatment times for STEMI.

METHODS

We conducted a study of all 747 nontransfer STEMI patients who underwent primary percutaneous coronary intervention (PCI) in Dallas County, Texas from October 1, 2010 through December 31, 2011. EMS leaders from 24 agencies and 15 major PCI receiving hospitals collected and shared common, de-identified patient data. We used 15 months of data to develop a generalized linear regression to assess the impact of EMS on two treatment metrics-hospital door to balloon (D2B) time, and symptom onset to arterial reperfusion (SOAR) time, a new metric we developed to assess total treatment times.

RESULTS

We found statistically significant reductions in median D2B (11.1-min reduction) and SOAR (63.5-min reduction) treatment times when EMS transported patients to the receiving facility, compared to self-transport. In addition, when trained EMS paramedics field-activated the cardiac catheterization laboratory using predefined specified protocols, D2B times were reduced by 38% (43 min) after controlling for confounding variables, and field activation was associated with a 21.9% reduction (73 min) in the mean SOAR time (both with p < 0.001).

CONCLUSION

Active EMS engagement in STEMI treatment was associated with significantly lower D2B and total coronary reperfusion times.

摘要

背景

减少治疗延迟是ST段抬高型心肌梗死(STEMI)急诊护理的关键目标。紧急医疗服务(EMS)是STEMI生存链的关键组成部分。

研究目的

我们试图评估将EMS作为一种改善STEMI全身治疗时间的策略进行精心整合的影响。

方法

我们对2010年10月1日至2011年12月31日在得克萨斯州达拉斯县接受直接经皮冠状动脉介入治疗(PCI)的所有747例非转运STEMI患者进行了一项研究。来自24个机构和15家主要PCI接收医院的EMS负责人收集并共享了通用的、去识别化的患者数据。我们使用15个月的数据建立了一个广义线性回归模型,以评估EMS对两个治疗指标的影响——医院门到球囊(D2B)时间,以及症状发作到动脉再灌注(SOAR)时间,这是我们为评估总治疗时间而开发的一个新指标。

结果

我们发现,与患者自行转运相比,当EMS将患者转运至接收机构时,D2B(减少11.1分钟)和SOAR(减少63.5分钟)治疗时间的中位数在统计学上有显著降低。此外,当经过培训的EMS护理人员按照预定义的特定方案在现场启动心脏导管实验室时,在控制混杂变量后,D2B时间减少了38%(43分钟),现场启动与平均SOAR时间减少21.9%(73分钟)相关(两者p<0.001)。

结论

EMS积极参与STEMI治疗与显著缩短D2B和总冠状动脉再灌注时间相关。

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