唇部恶性上皮样血管内皮瘤：一例报告及文献综述

Malignant epithelioid hemangioendothelioma of the lip: a case report and comprehensive literature review.

作者信息

Robinson Allen A, Tolentino Lucilene F, Uyanne Jettie, Melrose Raymond, Calhoun Colonya C

机构信息

Chief Resident, Division of Oral and Maxillofacial Surgery, Harbor-UCLA Medical Center, Torrance, CA.

Consulting Staff; Anatomic and Clinical Pathologist, Martin Luther King, Jr-Multiservice Ambulatory Care Center, Health Sciences; Assistant Clinical Professor III, David Geffen School of Medicine, UCLA, Los Angeles, CA; Clinical Assistant Professor, Charles Drew University of Medicine and Science, Los Angeles, CA; Pathology Consulting Staff Member, Rancho Los Amigos National Rehabilitation Center, Downey, CA.

出版信息

J Oral Maxillofac Surg. 2014 Apr;72(4):695-701. doi: 10.1016/j.joms.2013.09.027. Epub 2013 Nov 20.

DOI:10.1016/j.joms.2013.09.027

PMID:24268966

Abstract

Malignant epithelioid hemangioendothelioma (MEH), also known as high-risk epithelioid hemangioendothelioma, is a low- to intermediate-grade vascular malignancy originally described as a vascular neoplasm of endothelial origin. This very rare vascular neoplasm has been described mainly in soft tissue, but also in various organs and locations, including the liver, lung, brain, colon, lymph nodes, peritoneum, spleen, bone, skin, heart, soft tissues, and vascular system. Several cases have been described in the head and neck, including the submandibular gland, parotid gland, nasal cavity, parapharyngeal space, maxilla, maxillary sinus, occipital bone, oral cavity, thyroid gland, neck, scalp, larynx, and mandible. This case report is the first description of MEH presenting as an exophytic lower-lip lesion.

摘要

恶性上皮样血管内皮瘤（MEH），也称为高危上皮样血管内皮瘤，是一种低至中级别的血管恶性肿瘤，最初被描述为内皮起源的血管肿瘤。这种非常罕见的血管肿瘤主要见于软组织，但也见于各种器官和部位，包括肝脏、肺、脑、结肠、淋巴结、腹膜、脾脏、骨骼、皮肤、心脏、软组织和血管系统。头颈部已有数例报道，包括下颌下腺、腮腺、鼻腔、咽旁间隙、上颌骨、上颌窦、枕骨、口腔、甲状腺、颈部、头皮、喉和下颌骨。本病例报告首次描述了以唇外生性病变形式出现的MEH。