玻璃体内注射贝伐单抗治疗血管样条纹中的视网膜下新生血管膜
[Subretinal neovascular membrane in angioid streaks treated with intravitreal bevacizumab].
作者信息
García-López A, González-Castaño C
机构信息
Servicio de Oftalmología, Hospital Universitario Central de Asturias, Oviedo, Asturias, España.
Servicio de Oftalmología, Hospital Universitario Central de Asturias, Oviedo, Asturias, España.
出版信息
Arch Soc Esp Oftalmol. 2014 May;89(5):203-6. doi: 10.1016/j.oftal.2012.11.010. Epub 2013 Apr 3.
INTRODUCTION
Angioid streaks are breaks in Bruch's membrane that may be associated, among others, with pseudoxanthoma elasticum. Its most common complication is the development of subretinal neovascular membranes (SRNVM) and the decreased vision this entails.
CASE REPORT
A 28 year old woman with angioid streaks and SRNVM in the left eye, who received 3 injections of intravitreal bevacizumab, with rapid improvement in vision and stability during 11 months follow up. The finding of angioid streaks led to the diagnosis of pseudoxanthoma elasticum.
CONCLUSION
Intravitreal bevacizumab should be considered as an effective treatment option for choroidal neovascularization associated with angioid streaks.
引言
血管样条纹是布鲁赫膜的破裂，可能与弹性假黄瘤等有关。其最常见的并发症是视网膜下新生血管膜（SRNVM）的形成以及由此导致的视力下降。
病例报告
一名28岁女性，左眼有血管样条纹和SRNVM，接受了3次玻璃体内贝伐单抗注射，视力迅速改善，并在11个月的随访中保持稳定。血管样条纹的发现导致了弹性假黄瘤的诊断。
结论
玻璃体内贝伐单抗应被视为治疗与血管样条纹相关的脉络膜新生血管的有效选择。
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