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接受雄激素治疗的变性女性生殖道的组织学变化。

Histological changes in the genital tract in transsexual women following androgen therapy.

作者信息

Miller N, Bédard Y C, Cooter N B, Shaul D L

出版信息

Histopathology. 1986 Jul;10(7):661-9. doi: 10.1111/j.1365-2559.1986.tb02520.x.

DOI:10.1111/j.1365-2559.1986.tb02520.x
PMID:2427430
Abstract

Thirty-two young women who desired sexual reassignment were treated with large doses of androgen for a period of 1 year or more, followed by total hysterectomy. Histological examination revealed marked atrophy of cervical epithelium which could mimic dysplasia, and variable degrees of endometrial atrophy. The ovaries showed occasional corpora lutea indicating that even in the face of long term androgen therapy, ovulation may occur.

摘要

32名渴望进行性别重置的年轻女性接受了大剂量雄激素治疗,为期1年或更长时间,随后进行了全子宫切除术。组织学检查显示宫颈上皮明显萎缩,可类似发育异常,以及不同程度的子宫内膜萎缩。卵巢偶尔可见黄体,表明即使面对长期雄激素治疗,仍可能发生排卵。

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