小脑颗粒神经元前体细胞是出生后小脑中Hk2的来源。 - Suppr

Suppr

超能文献

Cerebellar granule neuron progenitors are the source of Hk2 in the postnatal cerebellum.

作者信息

Gershon Timothy R, Crowther Andrew J, Liu Hedi, Miller C Ryan, Deshmukh Mohanish

机构信息

Department of Neurology, University of North Carolina, Chapel Hill, NC 27599, USA.

出版信息

Cancer Metab. 2013 Jun 11;1(1):15. doi: 10.1186/2049-3002-1-15.

DOI:10.1186/2049-3002-1-15

PMID:24280296

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4178205/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1fce/4178205/b932f866613c/2049-3002-1-15-1.jpg

相似文献

Cerebellar granule neuron progenitors are the source of Hk2 in the postnatal cerebellum.小脑颗粒神经元前体细胞是出生后小脑中Hk2的来源。

Cancer Metab. 2013 Jun 11;1(1):15. doi: 10.1186/2049-3002-1-15.

Single-cell spatial transcriptomic analysis reveals common and divergent features of developing postnatal granule cerebellar cells and medulloblastoma.单细胞空间转录组分析揭示了出生后颗粒小脑细胞和髓母细胞瘤发育的共同和不同特征。

BMC Biol. 2021 Jul 1;19(1):135. doi: 10.1186/s12915-021-01071-8.

RBP-J is not required for granule neuron progenitor development and medulloblastoma initiated by Hedgehog pathway activation in the external germinal layer.RBP-J 对于 Hedgehog 通路激活引发的外胚层颗粒神经元祖细胞发育和髓母细胞瘤形成并非必需。

Neural Dev. 2010 Oct 15;5:27. doi: 10.1186/1749-8104-5-27.

The Transcriptional Regulator SnoN Promotes the Proliferation of Cerebellar Granule Neuron Precursors in the Postnatal Mouse Brain.转录调节因子 SnoN 促进出生后小鼠大脑小脑颗粒神经元前体细胞的增殖。

J Neurosci. 2019 Jan 2;39(1):44-62. doi: 10.1523/JNEUROSCI.0688-18.2018. Epub 2018 Nov 13.

Utilizing In Vivo Postnatal Electroporation to Study Cerebellar Granule Neuron Morphology and Synapse Development.利用体内产后电穿孔技术研究小脑颗粒神经元形态和突触发育。

J Vis Exp. 2021 Jun 9(172). doi: 10.3791/62568.

Granule neuron precursor cell proliferation is regulated by NFIX and intersectin 1 during postnatal cerebellar development.颗粒神经元前体细胞的增殖在出生后小脑发育过程中受到 NFIX 和 intersectin 1 的调节。

Brain Struct Funct. 2019 Mar;224(2):811-827. doi: 10.1007/s00429-018-1801-3. Epub 2018 Dec 3.

Deletion of CHD8 in cerebellar granule neuron progenitors leads to severe cerebellar hypoplasia, ataxia, and psychiatric behavior in mice.小脑颗粒神经元祖细胞中 CHD8 的缺失导致小鼠严重小脑发育不良、共济失调和精神行为异常。

J Genet Genomics. 2022 Sep;49(9):859-869. doi: 10.1016/j.jgg.2022.02.011. Epub 2022 Feb 26.

Potassium chloride inhibits proliferation of cerebellar granule neuron progenitors.

Brain Res Dev Brain Res. 1998 Mar 12;106(1-2):129-35. doi: 10.1016/s0165-3806(97)00204-6.

Dissociation of Cerebellar Granule Neuron Progenitors for Culture, FACS, Transcriptomics, and Molecular Biology.用于培养、荧光激活细胞分选、转录组学和分子生物学研究的小脑颗粒神经元祖细胞的解离

Methods Mol Biol. 2023;2583:3-7. doi: 10.1007/978-1-0716-2752-5_1.

Allocation of mouse cerebellar granule cells derived from embryonic ventricular progenitors--a study using a recombinant retrovirus.

Brain Res Dev Brain Res. 1993 Aug 20;74(2):245-52. doi: 10.1016/0165-3806(93)90010-8.

引用本文的文献

Emerging Functional Connections Between Metabolism and Epigenetic Remodeling in Neural Differentiation.神经分化中代谢与表观遗传重塑之间新兴的功能连接。

Mol Neurobiol. 2024 Sep;61(9):6688-6707. doi: 10.1007/s12035-024-04006-w. Epub 2024 Feb 10.

Pathological implications of metabolic reprogramming and its therapeutic potential in medulloblastoma.髓母细胞瘤中代谢重编程的病理意义及其治疗潜力

Front Cell Dev Biol. 2022 Oct 19;10:1007641. doi: 10.3389/fcell.2022.1007641. eCollection 2022.

Non-invasive Brain Delivery and Efficacy of BDNF in APP/PS1 Transgenic Mice as a Model of Alzheimer's Disease.以APP/PS1转基因小鼠为阿尔茨海默病模型的脑源性神经营养因子的非侵入性脑递送及其疗效

Med Res Arch. 2020 Feb;8(2). doi: 10.18103/mra.v8i2.2043.

Regulatory Role of Hexokinase 2 in Modulating Head and Neck Tumorigenesis.己糖激酶2在调节头颈部肿瘤发生中的调控作用

Front Oncol. 2020 Mar 3;10:176. doi: 10.3389/fonc.2020.00176. eCollection 2020.

Noninvasive Brain Delivery and Efficacy of BDNF to Stimulate Neuroregeneration and Suppression of Disease Relapse in EAE Mice.BDNF 通过非侵入性脑递送促进神经再生和抑制 EAE 小鼠疾病复发的疗效。

Mol Pharm. 2020 Feb 3;17(2):404-416. doi: 10.1021/acs.molpharmaceut.9b00644. Epub 2019 Dec 31.

Aspm sustains postnatal cerebellar neurogenesis and medulloblastoma growth in mice.在小鼠中，Aspm维持出生后小脑神经发生及髓母细胞瘤生长。

Development. 2015 Nov 15;142(22):3921-32. doi: 10.1242/dev.124271. Epub 2015 Oct 8.

Adaptations of energy metabolism during cerebellar neurogenesis are co-opted in medulloblastoma.髓母细胞瘤中采用了小脑神经发生过程中能量代谢的适应性变化。

Cancer Lett. 2015 Jan 28;356(2 Pt A):268-72. doi: 10.1016/j.canlet.2014.02.017. Epub 2014 Feb 22.

本文引用的文献

Hexokinase-2-mediated aerobic glycolysis is integral to cerebellar neurogenesis and pathogenesis of medulloblastoma.己糖激酶-2 介导的有氧糖酵解是小脑神经发生和髓母细胞瘤发病机制的重要组成部分。

Cancer Metab. 2013 Jan 23;1(1):2. doi: 10.1186/2049-3002-1-2.

Neuronal differentiation rescued by implantation of Weaver granule cell precursors into wild-type cerebellar cortex.将韦弗颗粒细胞前体植入野生型小脑皮质可挽救神经元分化。

Science. 1993 Apr 16;260(5106):367-9. doi: 10.1126/science.8469990.

Glial-guided granule neuron migration in vitro: a high-resolution time-lapse video microscopic study.体外神经胶质细胞引导的颗粒神经元迁移：一项高分辨率延时视频显微镜研究。

J Neurosci. 1987 Jun;7(6):1928-34. doi: 10.1523/JNEUROSCI.07-06-01928.1987.

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验