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生理和手术严重程度评分计算病死率和发病率的列线图(POSSUM)。

A nomogram to calculate the Physiological and Operative Severity Score for the enUmeration of Mortality and morbidity (POSSUM).

机构信息

Department of Anaesthetics, Welsh Centre for Burns, Abertawe Bro Morgannwg University NHS Trust, Swansea, UK.

出版信息

Br J Surg. 2014 Feb;101(3):239-45. doi: 10.1002/bjs.9363. Epub 2013 Nov 27.

Abstract

BACKGROUND

The Physiological and Operative Severity Score for the enUmeration of Mortality and morbidity (POSSUM) is a well validated model for the prediction of perioperative mortality and morbidity with application to surgery and intensive care medicine. The outcome measure calculations are time-consuming, complex and potentially error-prone. Nomograms are low-cost easy-to-use graphic devices that can be used to make repeated calculations to an acceptable level of accuracy for most clinical purposes. This paper describes a nomogram to aid calculation of POSSUM scores.

METHODS

This graphic solution consists of two sections: a tally sheet to calculate physiological and operative severity scores (PS and OS), and a nomogram to calculate mortality and morbidity. The latter was designed using standard mathematical methods, and drafted with the aid of commercially available software. Accuracy was confirmed by using a spreadsheet to generate 120 random sets of simulated values for PS and OS, and corresponding calculated values for predicted mortality and morbidity. The outcome values in each case were derived using the nomogram and compared with the spreadsheet values using Bland-Altman analysis.

RESULTS

Bland-Altman analysis showed close agreement between nomogram and spreadsheet. Bias of the nomogram was -0·1 percentage points for mortality and 0·1 percentage points for morbidity, with limits of agreement of -2·1 to +1·9 and -1·4 to +1·6 percentage points for mortality and morbidity respectively. Correlation coefficients were r > 0·999 and P < 0·001 for both mortality and morbidity.

CONCLUSION

The nomogram provides a rapid, accurate, low-cost means of performing, visualizing and cross-checking POSSUM calculations.

摘要

背景

生理和手术严重程度评分用于死亡率和发病率的枚举(POSSUM)是一种经过充分验证的模型,可用于预测手术和重症监护医学中的围手术期死亡率和发病率。结果测量计算繁琐、复杂且容易出错。列线图是一种低成本、易于使用的图形设备,可用于进行多次计算,以达到大多数临床目的可接受的准确性水平。本文介绍了一种列线图,以帮助计算 POSSUM 评分。

方法

这种图形解决方案由两部分组成:用于计算生理和手术严重程度评分(PS 和 OS)的计数表,以及用于计算死亡率和发病率的列线图。后者使用标准的数学方法设计,并借助商业上可用的软件起草。通过使用电子表格生成 PS 和 OS 的 120 组随机模拟值及其相应的预测死亡率和发病率的计算值,来确认准确性。在每种情况下,使用列线图和电子表格值之间的 Bland-Altman 分析来确定结果值。

结果

Bland-Altman 分析显示列线图和电子表格之间的一致性很好。死亡率的列线图偏差为 -0·1 个百分点,发病率的列线图偏差为 0·1 个百分点,死亡率和发病率的一致性界限分别为 -2·1 至 +1·9 和 -1·4 至 +1·6 个百分点。死亡率和发病率的相关系数均大于 0·999,P 值均小于 0·001。

结论

列线图提供了一种快速、准确、低成本的 POSSUM 计算方法,用于可视化和交叉检查。

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