Prytherch D R, Whiteley M S, Higgins B, Weaver P C, Prout W G, Powell S J
Department of Medical Physics, Portsmouth Hospitals NHS Trust, UK.
Br J Surg. 1998 Sep;85(9):1217-20. doi: 10.1046/j.1365-2168.1998.00840.x.
There is a need for an accurate measure of surgical outcomes so that hospitals and surgeons can be compared properly regardless of case mix. POSSUM (Physiological and Operative Severity Score for the enUmeration of Mortality and morbidity) uses a physiological score and an operative severity score to calculate risks of mortality and morbidity. In a previous small study it was found that Portsmouth POSSUM (P-POSSUM; a modification of the POSSUM system) provided a more accurate prediction of mortality.
Some 10000 general surgical interventions (excluding paediatric and day cases) were studied prospectively between August 1993 and November 1995. The POSSUM mortality equation was applied to the full 10000 surgical episodes. The 10000 patients were arranged in chronological order and the first 2500 were used as a training set to produce the modified P-POSSUM predictor equation. This was then applied prospectively to the remaining 7500 patients arranged chronologically in five groups of 1500.
The original POSSUM logistic regression equation for mortality overpredicts the overall risk of death by more than twofold and the risk of death for patients at lowest risk (5 per cent or less) by more than sevenfold. The P-POSSUM equation produced a very close fit with the observed in-hospital mortality.
P-POSSUM provides an accurate method for comparative surgical audit.
需要一种准确衡量手术结果的方法,以便能够在不考虑病例组合的情况下对医院和外科医生进行恰当比较。POSSUM(手术死亡率和发病率生理及手术严重程度评分系统)使用生理评分和手术严重程度评分来计算死亡和发病风险。在之前的一项小型研究中发现,朴茨茅斯POSSUM(P-POSSUM;POSSUM系统的一种改良版)对死亡率的预测更为准确。
在1993年8月至1995年11月期间,对约10000例普通外科手术(不包括儿科手术和日间手术)进行了前瞻性研究。将POSSUM死亡率方程应用于全部10000例手术病例。将这10000名患者按时间顺序排列,前2500名用作训练集,以得出改良后的P-POSSUM预测方程。然后将其前瞻性地应用于按时间顺序排列的其余7500名患者,分为五组,每组1500名。
原始的POSSUM死亡率逻辑回归方程对总体死亡风险的预测高估了两倍多,对最低风险患者(5%或更低)的死亡风险高估了七倍多。P-POSSUM方程与观察到的院内死亡率非常吻合。
P-POSSUM为外科手术比较审计提供了一种准确的方法。