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小儿呼吸体外生命支持的经济学与伦理学

Economics and ethics of paediatric respiratory extra corporeal life support.

作者信息

Callaghan M, Doyle Y, O'Hare B, Healy M, Nölke L

机构信息

Our Lady's Children's Hospital, Crumlin, Dublin 12.

出版信息

Ir Med J. 2013 Sep;106(8):252-3.

PMID:24282901
Abstract

Extra corporeal membrane oxygenation (ECMO) is a form of life support, which facilitates gas exchange outside the body via an oxygenator and a centrifugal pumping system. A paediatric cardiac ECMO programme was established in 2005 at Our Lady's Children's Hospital, Crumlin (OLCHC) and to date 75 patients have received ECMO, the majority being post operative cardiac patients. The outcome data compares favourably with international figures. ECMO has been most successful in the treatment of newborn infants with life threatening respiratory failure from conditions such as meconium aspiration, respiratory distress syndrome and respiratory infections. There is no formal paediatric respiratory ECMO programme at OLCHC, or anywhere else in Ireland. Currently, neonates requiring respiratory ECMO are transferred to centres in Sweden or the UK at an average cost of 133,000 Euros/infant, funded by the Health Service Executive E112 treatment abroad scheme. There is considerable morbidity associated with the transfer of critically ill infants, as well as significant psycho-social impact on families. OLCHC is not funded to provide respiratory ECMO, although the equipment and expertise required are similar to cardiac ECMO and are currently in place. The average cost of an ECMO run at OLCHC is 65,000 Euros. There is now a strong argument for a fully funded single national cardiac and respiratory paediatric ECMO centre, similar to that for adult patients.

摘要

体外膜肺氧合(ECMO)是一种生命支持形式,它通过氧合器和离心泵送系统在体外促进气体交换。2005年,克鲁姆林圣母儿童医院(OLCHC)建立了小儿心脏ECMO项目,迄今为止,已有75名患者接受了ECMO治疗,其中大多数是心脏手术后的患者。其结果数据与国际数据相比很有利。ECMO在治疗患有由胎粪吸入、呼吸窘迫综合征和呼吸道感染等疾病引起的危及生命的呼吸衰竭的新生儿方面最为成功。OLCHC或爱尔兰其他任何地方都没有正式的小儿呼吸ECMO项目。目前,需要呼吸ECMO的新生儿被转移到瑞典或英国的中心,平均费用为133,000欧元/婴儿,由卫生服务执行局的E112国外治疗计划资助。重症婴儿的转移会带来相当大的发病率,同时对家庭也有重大的心理社会影响。尽管所需的设备和专业知识与心脏ECMO相似且目前已具备,但OLCHC没有资金来提供呼吸ECMO。在OLCHC进行一次ECMO治疗的平均费用为65,000欧元。现在有一个强有力的理由支持建立一个由全额资助的单一国家小儿心脏和呼吸ECMO中心,类似于成人患者的中心。

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