Olaya Marcela, Vicioso Luis, Hierro Isabel, Quiñonero Antonio, Matilla Alfredo, López-Beltrán Antonio
Department of Pathology, Hospital Universitario Virgen de la Victoria, University of Malaga, Spain.
Anal Quant Cytopathol Histpathol. 2013 Oct;35(5):289-93.
Granular cell tumor is usually a benign tumor, generally believed to be of neural origin, most commonly affecting the tongue and skin. Although it can present in any part of the body, the bladder is a rare location, with only 16 cases found in the English-language literature.
We report the case of a 54-year-old woman with hematuria who had a solid tumor in the posterior wall of the bladder. Histological study of the samples obtained by transurethral resection revealed a granular cell tumor, confirmed by immunohistochemical techniques.
Granular cell tumors of the bladder are rare and generally benign but frequently present macroscopic features resembling those of urothelial carcinoma. The similarity can lead to an erroneous clinical diagnosis and unnecessary, aggressive treatment. A careful histopathological assessment is essential for an accurate diagnosis.
颗粒细胞瘤通常是一种良性肿瘤，一般认为起源于神经，最常累及舌头和皮肤。尽管它可出现在身体的任何部位，但膀胱是一个罕见的发病部位，英文文献中仅发现16例。
我们报告一例54岁血尿女性患者，其膀胱后壁有一个实性肿瘤。经尿道切除获取的样本进行组织学研究显示为颗粒细胞瘤，免疫组化技术证实了这一诊断。
膀胱颗粒细胞瘤罕见，通常为良性，但常常呈现出与尿路上皮癌相似的宏观特征。这种相似性可能导致错误的临床诊断以及不必要的积极治疗。仔细的组织病理学评估对于准确诊断至关重要。
