CT引导下恶性肺病变的粗针活检：需要穿刺几次？
CT-guided core biopsy of malignant lung lesions: how many needle passes are needed?
作者信息
Lim Chaehun, Lee Kyo Young, Kim Young Kyoon, Ko Jeong Min, Han Dae Hee
机构信息
Department of Radiology, Seoul St Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
出版信息
J Med Imaging Radiat Oncol. 2013 Dec;57(6):652-6. doi: 10.1111/1754-9485.12054. Epub 2013 Apr 1.
AIM
The study aims to determine the number of needle pass in the CT-guided core needle biopsy (CNB) in making a diagnosis of pulmonary malignancy.
MATERIALS AND METHODS
A total of 434 CNB records were retrospectively reviewed. The specimen obtained from each needle pass was put in a formalin container and then labelled for separate histopathological reporting. The patients were divided into five groups according to the total number of needle passes (n = 1, n = 2, n = 3, n = 4 and n ≥ 5). In each of the groups 2-4, it was analysed how many needle passes are required before a plateau in diagnostic yield is achieved.
RESULTS
CNB produced 283 true-positive and 23 false-negative diagnosis of malignancy. Cumulative sensitivity significantly (P < 0.05) increased between the first and second as well as the second and the third (if done) needle passes, but not between the third and fourth ones.
CONCLUSION
Three coaxial needle passes might be optimal in the diagnosis of lung malignancy.
目的
本研究旨在确定在CT引导下经皮肺穿刺活检（CNB）诊断肺恶性肿瘤时的进针次数。
材料与方法
回顾性分析434例CNB记录。每次进针获取的标本放入福尔马林容器中，然后标记以便单独进行组织病理学报告。根据进针总数将患者分为五组（n = 1、n = 2、n = 3、n = 4和n≥5）。在第2 - 4组中，分析在诊断率达到平稳之前需要进行多少次进针。
结果
CNB对恶性肿瘤做出了283例假阳性和23例假阴性诊断。累积敏感性在第一次和第二次以及第二次和第三次（如果进行了第三次）进针之间显著（P < 0.05）增加，但在第三次和第四次进针之间没有增加。
结论
在诊断肺恶性肿瘤时，三次同轴进针可能是最佳的。
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