Department of General Medicine, Waikato District Health Board, Hamilton, New Zealand.
J Thromb Haemost. 2014 Feb;12(2):214-9. doi: 10.1111/jth.12464.
There are few studies that directly compare the variation in incidence of venous thromboembolism (VTE) according to ethnicity.
The aim of this study was to compare the rates of VTE, deep venous thrombosis (DVT) and pulmonary embolism (PE) among different ethnic groups.
The cases diagnosed with VTE, DVT and PE for a period between March 2004 and June 2009 were identified through the hospital-based database system. The 2006 New Zealand Census data were used to calculate the rate of diagnosis.
The observed annual incidence of VTE during this period was 81.6 per 100000 population. The relative risks of VTE when comparing European subjects with Maori, Pacific Island and Asian subjects after age standardization were 1.98 (95% confidence interval [CI], 1.63-2.41), 3.22 (95% CI, 2.60-3.99) and 4.02 (95% CI, 3.34-4.84), respectively. Relative risks of DVT after age standardization when comparing European subjects with Maori, Pacific Island and Asian subjects, were 2.14 (95% CI, 1.72-2.66), 3.20 (95% CI, 2.46-4.17) and 4.75 (95% CI, 3.80-5.94), respectively. Indirect age standardization was used for comparison of the diagnosis of PE. The ratio between the calculated expected number of cases and the actual number of cases was 1.32 (95% CI, 0.89-1.75) for Maori subjects, 2.96 (95% CI, 1.89-4.03) for Pacific Islanders and 3.89 (95% CI, 3.00-4.78) for Asians.
Europeans have a significantly higher incidence of VTE compared with Maori, Pacific Island and Asian populations.
目前鲜有研究直接比较不同种族静脉血栓栓塞症（venous thromboembolism，VTE）发病率的差异。
本研究旨在比较不同种族静脉血栓栓塞症、深静脉血栓（deep venous thrombosis，DVT）和肺栓塞（pulmonary embolism，PE）的发生率。
通过医院的数据库系统，确定了 2004 年 3 月至 2009 年 6 月期间诊断为 VTE、DVT 和 PE 的病例。使用 2006 年新西兰人口普查数据计算诊断率。
在此期间，观察到 VTE 的年发病率为 81.6/100000 人。标准化年龄后，与欧洲人相比，毛利人、太平洋岛民和亚洲人的 VTE 相对风险分别为 1.98（95%置信区间[CI]，1.63-2.41）、3.22（95%CI，2.60-3.99）和 4.02（95%CI，3.34-4.84）。标准化年龄后，与欧洲人相比，毛利人、太平洋岛民和亚洲人的 DVT 相对风险分别为 2.14（95%CI，1.72-2.66）、3.20（95%CI，2.46-4.17）和 4.75（95%CI，3.80-5.94）。对 PE 的诊断采用间接年龄标准化进行比较。计算预期病例数与实际病例数的比值为毛利人 1.32（95%CI，0.89-1.75）、太平洋岛民 2.96（95%CI，1.89-4.03）和亚洲人 3.89（95%CI，3.00-4.78）。
与毛利人、太平洋岛民和亚洲人相比，欧洲人 VTE 的发病率明显更高。
