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在严重左心室功能障碍患者中,体外循环跳动心脏与常规冠状动脉旁路移植术进行血运重建:早期结果。

On-pump beating-heart versus conventional coronary artery bypass grafting for revascularization in patients with severe left ventricular dysfunction: early outcomes.

机构信息

From the Department of Cardiovascular Surgery, Erzurum Training and Research Hospital, Erzurum, Turkey.

出版信息

Can J Surg. 2013 Dec;56(6):398-404. doi: 10.1503/cjs.018412.

Abstract

BACKGROUND

We sought to evaluate the effects of on-pump beating-heart versus conventional coronary artery bypass grafting techniques requiring cardioplegic arrest in patients with coronary artery disease with left ventricular dysfunction.

METHODS

We report the early outcomes associated with survival, morbidity and improvement of left ventricular function in patients with low ejection fraction who underwent coronary artery bypass grafting between August 2009 and June 2012. Patients were separated into 2 groups: group I underwent conventional coronary artery bypass grafting and group II underwent an on-pump beating-heart technique without cardioplegic arrest.

RESULTS

In all, 131 patients underwent coronary artery bypass grafting: 66 in group I and 65 in group II. Left ventricular ejection fraction was 26.6% ± 3.5% in group I and 27.7% ± 4.7% in group II. Left ventricular end diastolic diameter was 65.6 ± 3.6 mm in group I and 64.1 ± 3.2 mm in group II. There was a significant reduction in mortality in the conventional and on-pump beating-heart groups (p < 0.001). Perioperative myocardial infarction and low cardiac output syndrome were higher in group I than group II (both p < 0.05). Improvement of left ventricular function after the surgical procedure was better in group II than group I.

CONCLUSION

The on-pump beating-heart technique is the preferred method for myocardial revascularization in patients with left ventricular dysfunction. This technique may be an acceptable alternative to the conventional technique owing to lower postoperative mortality and morbidity.

摘要

背景

我们旨在评估在左心室功能障碍的冠心病患者中,使用不停跳心脏跳动与需要心脏停搏的传统冠状动脉旁路移植术的效果。

方法

我们报告了 2009 年 8 月至 2012 年 6 月期间接受冠状动脉旁路移植术的低射血分数患者的生存、发病率和左心室功能改善相关的早期结果。患者分为两组:I 组行传统冠状动脉旁路移植术,II 组行不停跳心脏跳动术而无需心脏停搏。

结果

共有 131 例患者接受冠状动脉旁路移植术:I 组 66 例,II 组 65 例。I 组左心室射血分数为 26.6%±3.5%,II 组为 27.7%±4.7%。I 组左心室舒张末期直径为 65.6±3.6mm,II 组为 64.1±3.2mm。在传统和不停跳心脏跳动组中死亡率均显著降低(p<0.001)。I 组围手术期心肌梗死和低心排综合征发生率高于 II 组(均 p<0.05)。术后左心室功能改善在 II 组优于 I 组。

结论

在左心室功能障碍患者中,体外循环心脏跳动技术是心肌血运重建的首选方法。由于术后死亡率和发病率较低,该技术可能是传统技术的可接受替代方法。

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