焦虑症与快速循环：来自8129名双相情感障碍青少年队列的数据。
Anxiety disorders and rapid cycling: data from a cohort of 8129 youths with bipolar disorder.
作者信息
Castilla-Puentes Ruby, Sala Regina, Ng Bernardo, Galvez Juan, Camacho Alvaro
机构信息
*Temple University, Fort Washington, PA; †Institute of Psychiatry, King's College London, London, UK; ‡Sun Valley Behavioral & Research Center, Imperial, CA; §Pontificia Universidad Javeriana, Bogota, Colombia; and ∥University of California, San Diego, CA.
出版信息
J Nerv Ment Dis. 2013 Dec;201(12):1060-5. doi: 10.1097/NMD.0000000000000052.
Anxiety disorders (ADs) are common in youths with bipolar disorder (BD). We examine psychiatric comorbidity, hospitalization, and treatment in youths with versus without AD and rapid cycling (four or more cycles per year). Data from the Integrated Healthcare Information Services cohort were used and included 8129 youths (ages ≤18 years). Prevalence of AD, demographic, type of AD, hospitalization, and use of psychotropics were compared between rapid and nonrapid cycling. Overall, 51% of the youths met criteria for at least one comorbid AD; they were predominantly female and were between 12 and 17 years of age. The most common comorbid ADs were generalized ADs and separation ADs. In the patients with rapid cycling, 65.5% met criteria for comorbid AD. The BD youths with AD were more likely to have major depressive disorders and other comorbid ADs, to be given more psychotropics, and to be hospitalized for depression and medical conditions more often than were those without AD.
焦虑症（ADs）在双相情感障碍（BD）青少年中很常见。我们研究了合并或未合并AD以及快速循环（每年四个或更多发作周期）的青少年的精神共病、住院情况和治疗情况。使用了综合医疗信息服务队列的数据，其中包括8129名青少年（年龄≤18岁）。比较了快速循环组和非快速循环组之间AD的患病率、人口统计学特征、AD类型、住院情况和精神药物的使用情况。总体而言，51%的青少年符合至少一种共病AD的标准；他们主要为女性，年龄在12至17岁之间。最常见的共病AD是广泛性焦虑症和分离性焦虑症。在快速循环患者中，65.5%符合共病AD的标准。与未患AD的BD青少年相比，患AD的BD青少年更易患重度抑郁症和其他共病AD，更常使用精神药物，因抑郁症和身体疾病住院的频率也更高。
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