Veering M M, Jonkman E J, Poortvliet D C, De Weerd A W, Tans J T, John E R
Electroencephalogr Clin Neurophysiol. 1986 Nov;64(5):383-93. doi: 10.1016/0013-4694(86)90071-4.
Follow-up studies over a period of 3 months were carried out on 100 patients with a unilateral ischaemia in the territory of the middle cerebral artery. Twenty-six patients underwent an STA-MCA bypass operation and 23 patients, a carotid endarterectomy. Fifty-one unoperated patients served as a reference group. A clinical examination, quantitative electroencephalogram (qEEG) and cerebral blood flow study (CBF) were performed before, 2 weeks after and 3 months after surgery. In the unoperated patients these examinations were carried out shortly after admission, 3 weeks later and 3 months thereafter. In the unoperated group, a highly significant improvement of clinical score and qEEG was found, but there were no changes in CBF values. The bypass patients showed a transient deterioration of clinical score and qEEG after surgery. Further, over the 3 month post-operative period, the bypass patients and the endarterectomy patients showed no improvement in CBF and qEEG. Thus, a beneficial effect of reconstructive surgery over the period studied could not be demonstrated.
对100例大脑中动脉供血区单侧缺血患者进行了为期3个月的随访研究。26例患者接受了颞浅动脉-大脑中动脉搭桥手术,23例患者接受了颈动脉内膜切除术。51例未手术患者作为参照组。在手术前、术后2周和术后3个月进行了临床检查、定量脑电图(qEEG)和脑血流研究(CBF)。在未手术患者中,这些检查在入院后不久、3周后及此后3个月进行。在未手术组中,临床评分和qEEG有显著改善,但CBF值无变化。搭桥手术患者术后临床评分和qEEG出现短暂恶化。此外,在术后3个月期间,搭桥手术患者和内膜切除术患者的CBF和qEEG均未改善。因此,在所研究的时间段内,未能证明重建手术有有益效果。