Binnie C D, Prior P F
Department of Clinical Neurophysiology, The Maudsley Hospital, Denmark Hill, London, UK.
J Neurol Neurosurg Psychiatry. 1994 Nov;57(11):1308-19. doi: 10.1136/jnnp.57.11.1308.
Notwithstanding recent advances in neuroimaging, EEG remains a major technique for investigation of the brain. Its main applications are in assessment of cerebral function rather than for detecting structural abnormalities. The principal clinical applications are in epilepsy, states of altered consciousness including postanoxic and traumatic coma, the parasomnias, dementias, toxic confusional states, cerebral infections, and various other encephalopathies. Abnormalities in EEG reflect general pathophysiological processes, raised intracranial pressure, cerebral anoxia, or oedema, epileptogenesis etc, and show little specificity for a particular disease. Consequently, they need to be interpreted in a particular clinical context; the use of routine EEG examination for screening purposes is rarely of value. Conversely, the investigation becomes most cost effective when applied to specific problems--for instance, monitoring serial changes in postanoxic coma or during open heart surgery, differential diagnosis (by telemetric ictal recordings) of epileptic and non-epileptic attacks, and providing early prediction of outcome after stroke. High technological standards and an individualised problem solving approach are prerequisites of a cost effective, reliable clinical EEG service. These are most likely to be achieved by a considered, selective referral policy, the use where necessary of prolonged complex procedures such as telemetry, and the avoidance of routine examinations of dubious clinical relevance.
尽管神经影像学技术最近取得了进展,但脑电图(EEG)仍然是研究大脑的主要技术。其主要应用在于评估脑功能,而非检测结构异常。主要临床应用包括癫痫、意识改变状态,包括缺氧后和创伤性昏迷、异态睡眠、痴呆、中毒性谵妄状态、脑部感染以及各种其他脑病。脑电图异常反映了一般病理生理过程、颅内压升高、脑缺氧或水肿、癫痫发生等情况,对特定疾病的特异性较低。因此,需要在特定临床背景下进行解读;将常规脑电图检查用于筛查目的很少有价值。相反,当应用于特定问题时,该检查最具成本效益,例如监测缺氧后昏迷或心脏直视手术期间的系列变化、癫痫发作和非癫痫发作的鉴别诊断(通过遥测发作期记录)以及提供中风后预后的早期预测。高技术标准和个性化的问题解决方法是具有成本效益、可靠临床脑电图服务的先决条件。这些最有可能通过深思熟虑的选择性转诊政策、必要时使用遥测等延长的复杂程序以及避免进行临床相关性存疑的常规检查来实现。