You Tsung-Zoo, Wang Shou-Jen, Young Yi-Ho
* Department of Otolaryngology, Catholic Cardinal Tien Hospital, Fu-Jen Catholic University , Taipei , Taiwan.
Int J Audiol. 2014 Mar;53(3):153-8. doi: 10.3109/14992027.2013.851798. Epub 2013 Nov 28.
An inner ear test battery comprising audiometry and ocular vestibular-evoked myogenic potential (oVEMP), cervical VEMP (cVEMP), and caloric tests was applied to patients with sudden deafness to map their lesions and predict hearing outcome.
Retrospective study.
Seventy-five patients with unilateral sudden deafness underwent an inner-ear test battery. Registering the grades of sudden deafness was based on the number of abnormal test results in the inner ear test battery.
After treatment for three consecutive months, mean hearing gain declined significantly from Grade I (one abnormal test) to Grade IV (four abnormal tests). Significant relations existed between hearing outcome and oVEMP test results (p < 0.05), caloric test results (p < 0.05), but not cVEMP test results and pre-treatment mean hearing level. Combined caloric and oVEMP test results demonstrated a stronger predictor with a c statistic of 0.722 than either test alone, indicating that this regression model fits the whole set of observations well and is effective in predicting the hearing outcome.
Abnormal caloric and oVEMP test results in sudden deafness patients may indicate poor prognosis for hearing improvement, whereas hearing recovery can be anticipated when both tests reveal normal responses.
对突发性聋患者应用一套包括听力测定、眼震前庭诱发肌源性电位（oVEMP）、颈肌前庭诱发肌源性电位（cVEMP）及冷热试验的内耳检查组合，以明确其病变并预测听力转归。
回顾性研究。
75例单侧突发性聋患者接受了一套内耳检查组合。根据内耳检查组合中异常检查结果的数量对突发性聋的分级进行记录。
连续治疗3个月后，平均听力增益从I级（一项异常检查）到IV级（四项异常检查）显著下降。听力转归与oVEMP检查结果（p<0.05）、冷热试验结果（p<0.05）存在显著相关性，但与cVEMP检查结果及治疗前平均听力水平无关。冷热试验和oVEMP检查结果联合显示，其预测能力更强，c统计量为0.722，优于单独任何一项检查，表明该回归模型能很好地拟合全部观察结果，且在预测听力转归方面有效。
突发性聋患者冷热试验及oVEMP检查结果异常可能提示听力改善预后不良，而两项检查均显示正常反应时则可预期听力恢复。
