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用辣根过氧化物酶标记凝集素的逆行和顺行运输法研究猫齿状红核纤维的起源与终止

The origin and termination of the dentatorubral fibres in the cat as studied with retrograde and anterograde transport of peroxidase labelled lectin.

作者信息

Walberg F, Dietrichs E, Nordby T

出版信息

Exp Brain Res. 1986;63(2):294-300. doi: 10.1007/BF00236846.

DOI:10.1007/BF00236846
PMID:2428653
Abstract

The dentatorubral projection in the cat was studied by means of retrograde and anterograde transport after implantations of crystalline wheat germ agglutinin-horseradish peroxidase (WGA-HRP) in the red and dentate nuclei, respectively. Our retrograde transport findings give evidence that rubral afferents originate in the contralateral dentate nucleus, mainly dorsally in its central part. The dentate implantations (with no contamination of the adjacent interposed nuclei) show that in the cat the great majority of the dentatofugal fibres leave the ipsilateral brachium conjunctivum to decussate below the red nucleus. Scattered crossing fibres also penetrate the contralateral red nucleus at all caudorostral levels on their way to the contralateral thalamus. Terminal fibres were found only in the rostral part of the red nucleus, but no retrogradely labelled rubral cells were observed. The findings are discussed in relation to previous studies on the dentatorubral projection.

摘要

分别在猫的红核和齿状核中植入结晶性小麦胚凝集素-辣根过氧化物酶(WGA-HRP)后,通过逆行和顺行运输研究了猫的齿状核红核投射。我们的逆行运输研究结果表明,红核传入纤维起源于对侧齿状核,主要起源于其中心部分的背侧。齿状核植入(不污染相邻的中介核)表明,在猫中,绝大多数齿状核传出纤维离开同侧结合臂,在红核下方交叉。在向对侧丘脑行进的过程中,分散的交叉纤维在所有尾-嘴侧水平也穿过对侧红核。仅在红核的嘴侧部分发现了终末纤维,但未观察到逆行标记的红核细胞。结合先前关于齿状核红核投射的研究对这些发现进行了讨论。

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The origin and termination of the dentatorubral fibres in the cat as studied with retrograde and anterograde transport of peroxidase labelled lectin.用辣根过氧化物酶标记凝集素的逆行和顺行运输法研究猫齿状红核纤维的起源与终止
Exp Brain Res. 1986;63(2):294-300. doi: 10.1007/BF00236846.
2
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Brain Res Bull. 1981 Jan;6(1):19-22. doi: 10.1016/s0361-9230(81)80065-2.
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Is lectin-coupled horseradish peroxidase taken up and transported by undamaged as well as by damaged fibers in the central nervous system?凝集素偶联的辣根过氧化物酶在中枢神经系统中能否被未受损的纤维以及受损的纤维摄取和转运?
Brain Res. 1983 Nov 14;278(1-2):1-9. doi: 10.1016/0006-8993(83)90221-4.
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