Department of Plastic Surgery, Georgetown School of Medicine, Center for Wound Healing & Hyperbaric Medicine, MedStar Georgetown University Hospital, 3800 Reservoir Road Northwest, Washington, DC 20007, USA.
Endocrinol Metab Clin North Am. 2013 Dec;42(4):833-47. doi: 10.1016/j.ecl.2013.08.002.
The diabetic foot is at high risk for complications because of its role in ambulation. Peripheral neuropathy and peripheral vascular disease can lead to chronic foot ulcers, which are at high risk for infection, in part attributable to areas of high pressure caused by lack of tolerance of the soft tissue and bone and joint deformity. If left untreated, infection and ischemia lead to tissue death, culminating in amputation. Treatment strategies include antibiosis, topical therapies, offloading, debridement, and surgery. A multidisciplinary team approach is necessary in the prevention and treatment of complications of the diabetic foot.
糖尿病足由于其在步行中的作用而面临高并发症风险。周围神经病变和周围血管疾病可导致慢性足部溃疡，这些溃疡极易感染，部分原因是由于软组织和骨骼关节畸形导致无法耐受而产生的高压区域。如果不进行治疗，感染和缺血会导致组织死亡，最终导致截肢。治疗策略包括抗菌治疗、局部治疗、减压、清创和手术。在预防和治疗糖尿病足并发症方面，需要多学科团队方法。
