HIV & STI Department, Centre for Infectious Disease Surveillance and Control,Public Health England,UK.
Centre for HIV & STIs, National Institute for Communicable Diseases,National Health Laboratory Service,Johannesburg,South Africa.
Epidemiol Infect. 2014 Aug;142(8):1678-87. doi: 10.1017/S0950268813002902. Epub 2013 Nov 29.
We used data from the Genitourinary Medicine Clinic Activity Dataset (GUMCAD) over a 3-year period (2009-2011) to investigate the distribution and risk factors of Trichomonas vaginalis infection in England. Socio-demographic and clinical risk factors associated with a diagnosis of T. vaginalis were explored using multivariable logistic regression. Rates of T. vaginalis infection were highest in London and the West Midlands. For men and women, T. vaginalis infection was significantly associated with: older age compared to those aged 20-24 years, non-white ethnicity (in particular black Caribbean and black 'other' ethnic groups), and birth in the Caribbean vs. birth in the UK. Current gonorrhoea or chlamydia infection was associated with a diagnosis of T. vaginalis in women. Further research is required to assess the public health impact and cost-effectiveness of introducing targeted screening for women at high risk of infection in areas of higher prevalence.
我们使用了为期 3 年(2009-2011 年)的泌尿生殖医学门诊活动数据集(GUMCAD)的数据,来调查英格兰阴道毛滴虫感染的分布和危险因素。使用多变量逻辑回归探讨了与阴道毛滴虫病诊断相关的社会人口学和临床危险因素。伦敦和西米德兰兹地区的阴道毛滴虫感染率最高。对于男性和女性,阴道毛滴虫感染与以下因素显著相关:与 20-24 岁人群相比,年龄较大、非白色人种(特别是加勒比黑人及其他黑人族群)、以及在加勒比地区出生而非在英国出生。目前患有淋病或衣原体感染的女性更易被诊断为阴道毛滴虫病。需要进一步研究以评估在感染率较高的地区,针对高风险感染女性进行有针对性筛查的公共卫生影响和成本效益。