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Systems biology and the analysis of genetic variation.

作者信息

Sunyaev Shamil R, Roth Frederick P

机构信息

Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, MA 02115, USA.

出版信息

Curr Opin Genet Dev. 2013 Dec;23(6):599-601. doi: 10.1016/j.gde.2013.11.010. Epub 2013 Nov 28.

DOI:10.1016/j.gde.2013.11.010

PMID:24291212

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4116483/

Abstract

摘要

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Should evolutionary geneticists worry about higher-order epistasis?

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Using chromatin marks to interpret and localize genetic associations to complex human traits and diseases.

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Contemporary, yeast-based approaches to understanding human genetic variation.

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相似文献

Systems biology and the analysis of genetic variation.

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Methods Mol Biol. 2017;1488:337-362. doi: 10.1007/978-1-4939-6427-7_16.

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Trends Genet. 2021 Jul;37(7):631-638. doi: 10.1016/j.tig.2021.03.005. Epub 2021 Apr 21.

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Mamm Genome. 2007 Jul;18(6-7):383-8. doi: 10.1007/s00335-007-9044-2. Epub 2007 Aug 1.

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Nat Rev Genet. 2009 Sep;10(9):651-7. doi: 10.1038/nrg2617. Epub 2009 Jul 28.

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Trends Genet. 2019 Jan;35(1):55-67. doi: 10.1016/j.tig.2018.10.004. Epub 2018 Nov 20.

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Nat Rev Genet. 2014 Jan;15(1):34-48. doi: 10.1038/nrg3575. Epub 2013 Dec 3.

本文引用的文献

Universality and predictability in molecular quantitative genetics.

Curr Opin Genet Dev. 2013 Dec;23(6):684-93. doi: 10.1016/j.gde.2013.11.001. Epub 2013 Nov 28.

Should evolutionary geneticists worry about higher-order epistasis?

Curr Opin Genet Dev. 2013 Dec;23(6):700-7. doi: 10.1016/j.gde.2013.10.007. Epub 2013 Nov 27.

Edgotype: a fundamental link between genotype and phenotype.

Curr Opin Genet Dev. 2013 Dec;23(6):649-57. doi: 10.1016/j.gde.2013.11.002. Epub 2013 Nov 26.

Genetic architecture of quantitative traits and complex diseases.

Curr Opin Genet Dev. 2013 Dec;23(6):678-83. doi: 10.1016/j.gde.2013.10.008. Epub 2013 Nov 26.

Using chromatin marks to interpret and localize genetic associations to complex human traits and diseases.

Curr Opin Genet Dev. 2013 Dec;23(6):635-41. doi: 10.1016/j.gde.2013.10.009. Epub 2013 Nov 25.

Network analysis of GWAS data.

Curr Opin Genet Dev. 2013 Dec;23(6):602-10. doi: 10.1016/j.gde.2013.09.003. Epub 2013 Nov 26.

The molecular basis of phenotypic variation in yeast.

Curr Opin Genet Dev. 2013 Dec;23(6):672-7. doi: 10.1016/j.gde.2013.10.005. Epub 2013 Nov 21.

The spectrum of mutations controlling complex traits and the genetics of fitness in plants.

Curr Opin Genet Dev. 2013 Dec;23(6):665-71. doi: 10.1016/j.gde.2013.10.006. Epub 2013 Nov 20.

Contemporary, yeast-based approaches to understanding human genetic variation.

Curr Opin Genet Dev. 2013 Dec;23(6):658-64. doi: 10.1016/j.gde.2013.10.001. Epub 2013 Nov 16.

Promises and limitations of hitchhiking mapping.

Curr Opin Genet Dev. 2013 Dec;23(6):694-9. doi: 10.1016/j.gde.2013.10.002. Epub 2013 Nov 12.

Suppr超能文献

Systems biology and the analysis of genetic variation.

作者信息

机构信息

出版信息

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