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Purification of double-stranded RNA-dependent protein kinase from mouse fibroblasts.

作者信息

Samuel C E, Knutson G S, Berry M J, Atwater J A, Lasky S R

出版信息

Methods Enzymol. 1986;119:499-516. doi: 10.1016/0076-6879(86)19070-7.

DOI:10.1016/0076-6879(86)19070-7
PMID:2429153
Abstract
摘要

相似文献

1
Purification of double-stranded RNA-dependent protein kinase from mouse fibroblasts.从小鼠成纤维细胞中纯化双链RNA依赖性蛋白激酶
Methods Enzymol. 1986;119:499-516. doi: 10.1016/0076-6879(86)19070-7.
2
An interferon-induced, ribosome-associated protein kinase which reduces the activity of initiation factor.一种干扰素诱导的、与核糖体相关的蛋白激酶，它可降低起始因子的活性。
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Two interferon-induced proteins are involved in the protein kinase complex dependent on double-stranded RNA.两种干扰素诱导蛋白参与依赖双链RNA的蛋白激酶复合物。
Cell. 1985 Dec;43(3 Pt 2):685-94. doi: 10.1016/0092-8674(85)90241-7.
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Xenopus ribosomal protein S6 kinase II.非洲爪蟾核糖体蛋白S6激酶II
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Purification of protein kinases that phosphorylate the repetitive carboxyl-terminal domain of eukaryotic RNA polymerase II.
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Double-stranded RNA dependent protein kinase (s) in rabbit reticulocyte lysates analogous to kinase from interferon-treated cells.兔网织红细胞裂解物中与干扰素处理细胞中的激酶类似的双链RNA依赖性蛋白激酶。
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Purification of Drosophila cAMP-dependent protein kinase.果蝇环磷酸腺苷依赖性蛋白激酶的纯化
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Dissociation of protein kinase activity and the induction of the antiviral state in a cell line responsive to the antiviral effects of interferon.
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Characterization of the interferon-induced double-stranded RNA-dependent protein kinase and its possible role in the antiviral action of interferon.干扰素诱导的双链RNA依赖性蛋白激酶的特性及其在干扰素抗病毒作用中的可能作用。
Prog Clin Biol Res. 1985;202:247-54.
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Purification of smooth muscle myosin light-chain kinase.平滑肌肌球蛋白轻链激酶的纯化
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引用本文的文献

1
Phosphorylation of the RNA-dependent protein kinase regulates its RNA-binding activity.依赖RNA的蛋白激酶的磷酸化作用调节其RNA结合活性。
Nucleic Acids Res. 2001 Jul 15;29(14):3020-9. doi: 10.1093/nar/29.14.3020.
2
Mutant influenza viruses with a defective NS1 protein cannot block the activation of PKR in infected cells.具有缺陷型NS1蛋白的突变流感病毒无法阻断受感染细胞中PKR的激活。
J Virol. 1999 Mar;73(3):2425-33. doi: 10.1128/JVI.73.3.2425-2433.1999.
3
Double-stranded RNA-activated protein kinase (PKR) is negatively regulated by 60S ribosomal subunit protein L18.
双链RNA激活蛋白激酶（PKR）受60S核糖体亚基蛋白L18的负调控。
Mol Cell Biol. 1999 Feb;19(2):1116-25. doi: 10.1128/MCB.19.2.1116.
4
Identification and characterization of pancreatic eukaryotic initiation factor 2 alpha-subunit kinase, PEK, involved in translational control.参与翻译调控的胰腺真核起始因子2α亚基激酶PEK的鉴定与特性分析
Mol Cell Biol. 1998 Dec;18(12):7499-509. doi: 10.1128/MCB.18.12.7499.
5
In vitro analysis of virus-associated RNA I (VAI RNA): inhibition of the double-stranded RNA-activated protein kinase PKR by VAI RNA mutants correlates with the in vivo phenotype and the structural integrity of the central domain.病毒相关RNA I（VAI RNA）的体外分析：VAI RNA突变体对双链RNA激活蛋白激酶PKR的抑制作用与体内表型及中央结构域的结构完整性相关。
J Virol. 1994 Jul;68(7):4137-51. doi: 10.1128/JVI.68.7.4137-4151.1994.
6
The mouse antiphosphotyrosine immunoreactive kinase, TIK, is indistinguishable from the double-stranded RNA-dependent, interferon-induced protein kinase, PKR.小鼠抗磷酸酪氨酸免疫反应性激酶TIK与双链RNA依赖性干扰素诱导蛋白激酶PKR无法区分。
Nucleic Acids Res. 1993 Oct 11;21(20):4830-5. doi: 10.1093/nar/21.20.4830.
7
Mechanism of interferon action: evidence for intermolecular autophosphorylation and autoactivation of the interferon-induced, RNA-dependent protein kinase PKR.干扰素作用机制：干扰素诱导的RNA依赖性蛋白激酶PKR分子间自磷酸化和自激活的证据
J Virol. 1993 Dec;67(12):7695-700. doi: 10.1128/JVI.67.12.7695-7700.1993.
8
Double-stranded-RNA-dependent protein kinase and TAR RNA-binding protein form homo- and heterodimers in vivo.双链RNA依赖的蛋白激酶与反式激活应答元件RNA结合蛋白在体内形成同二聚体和异二聚体。
Proc Natl Acad Sci U S A. 1995 Oct 10;92(21):9445-9. doi: 10.1073/pnas.92.21.9445.
9
Mechanism of interferon action: characterization of the intermolecular autophosphorylation of PKR, the interferon-inducible, RNA-dependent protein kinase.干扰素作用机制：PKR（干扰素诱导的RNA依赖性蛋白激酶）分子间自磷酸化的特性
J Virol. 1995 Aug;69(8):5195-8. doi: 10.1128/JVI.69.8.5195-5198.1995.
10
Reversal of the interferon-sensitive phenotype of a vaccinia virus lacking E3L by expression of the reovirus S4 gene.通过呼肠孤病毒S4基因的表达逆转缺乏E3L的痘苗病毒的干扰素敏感表型。
J Virol. 1995 Jan;69(1):499-505. doi: 10.1128/JVI.69.1.499-505.1995.