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1
Heat shock factor 1 confers resistance to Hsp90 inhibitors through p62/SQSTM1 expression and promotion of autophagic flux.
Biochem Pharmacol. 2014 Feb 1;87(3):445-55. doi: 10.1016/j.bcp.2013.11.014. Epub 2013 Nov 28.
2
Molecular stress-inducing compounds increase osteoclast formation in a heat shock factor 1 protein-dependent manner.
J Biol Chem. 2014 May 9;289(19):13602-14. doi: 10.1074/jbc.M113.530626. Epub 2014 Apr 1.
3
Targeting SQSTM1/p62 induces cargo loading failure and converts autophagy to apoptosis via NBK/Bik.
Mol Cell Biol. 2014 Sep 15;34(18):3435-49. doi: 10.1128/MCB.01383-13. Epub 2014 Jul 7.
4
Activation of heat shock factor 1 plays a role in pyrrolidine dithiocarbamate-mediated expression of the co-chaperone BAG3.
Int J Biochem Cell Biol. 2010 Nov;42(11):1856-63. doi: 10.1016/j.biocel.2010.07.021. Epub 2010 Aug 6.
6
HSF1 stress response pathway regulates autophagy receptor SQSTM1/p62-associated proteostasis.
Autophagy. 2017 Jan 2;13(1):133-148. doi: 10.1080/15548627.2016.1248018. Epub 2016 Nov 15.
7
Targeting HSF1 sensitizes cancer cells to HSP90 inhibition.
Oncotarget. 2013 Jun;4(6):816-29. doi: 10.18632/oncotarget.991.
8
HSP90 interacts with and regulates the activity of heat shock factor 1 in Xenopus oocytes.
Mol Cell Biol. 1998 Sep;18(9):4949-60. doi: 10.1128/MCB.18.9.4949.

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KRIBB11 Exerts Anticancer Effects on A172 Glioblastoma Cells the Cdh1/SKP2/p27 and HSF1/p53/p21 Pathways.
Cancer Genomics Proteomics. 2025 May-Jun;22(3):467-477. doi: 10.21873/cgp.20514.
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C-terminal domain dimerization in yeast Hsp90 is moderately modulated by the other domains.
Biophys J. 2024 Jan 16;123(2):172-183. doi: 10.1016/j.bpj.2023.12.005. Epub 2023 Dec 10.
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Roles of Stress Response in Autophagy Processes and Aging-Related Diseases.
Int J Mol Sci. 2023 Sep 7;24(18):13804. doi: 10.3390/ijms241813804.
8
HSF1 Attenuates the Release of Inflammatory Cytokines Induced by Lipopolysaccharide through Transcriptional Regulation of .
Microbiol Spectr. 2023 Feb 14;11(1):e0305922. doi: 10.1128/spectrum.03059-22. Epub 2023 Jan 4.
9
HSF1 and Its Role in Huntington's Disease Pathology.
Adv Exp Med Biol. 2023;1410:35-95. doi: 10.1007/5584_2022_742.
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HSP90 inhibitors and cancer: Prospects for use in targeted therapies (Review).
Oncol Rep. 2023 Jan;49(1). doi: 10.3892/or.2022.8443. Epub 2022 Nov 11.

本文引用的文献

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Knockdown of p62/sequestosome 1 attenuates autophagy and inhibits colorectal cancer cell growth.
Mol Cell Biochem. 2014 Jan;385(1-2):95-102. doi: 10.1007/s11010-013-1818-0. Epub 2013 Sep 25.
2
Accumulation of p62 is associated with poor prognosis in patients with triple-negative breast cancer.
Onco Targets Ther. 2013 Jul 19;6:883-8. doi: 10.2147/OTT.S46222. Print 2013.
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Acetylated hsp70 and KAP1-mediated Vps34 SUMOylation is required for autophagosome creation in autophagy.
Proc Natl Acad Sci U S A. 2013 Apr 23;110(17):6841-6. doi: 10.1073/pnas.1217692110. Epub 2013 Apr 8.
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Why should autophagic flux be assessed?
Acta Pharmacol Sin. 2013 May;34(5):595-9. doi: 10.1038/aps.2012.184. Epub 2013 Mar 11.
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A modified HSP70 inhibitor shows broad activity as an anticancer agent.
Mol Cancer Res. 2013 Mar;11(3):219-29. doi: 10.1158/1541-7786.MCR-12-0547-T. Epub 2013 Jan 9.
8
A prescription for 'stress'--the role of Hsp90 in genome stability and cellular adaptation.
Trends Cell Biol. 2012 Nov;22(11):576-83. doi: 10.1016/j.tcb.2012.08.006. Epub 2012 Sep 4.
10
The autophagy-associated factors DRAM1 and p62 regulate cell migration and invasion in glioblastoma stem cells.
Oncogene. 2013 Feb 7;32(6):699-712. doi: 10.1038/onc.2012.111. Epub 2012 Apr 23.

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