Division of Mental Health, Norwegian Institute of Public Health, Bergen, Norway,
Eur Child Adolesc Psychiatry. 2014 Aug;23(8):681-9. doi: 10.1007/s00787-013-0502-y. Epub 2013 Nov 30.
Both sleep problems and depression are common problems in adolescence, but well-defined large epidemiological studies on the relationship are missing in this age group. The aim of this study was to examine the association between depression and several sleep parameters, including insomnia, in a population-based study of adolescents aged 16-18 years, and to explore potential gender differences. A large population-based study in Hordaland County in Norway conducted in 2012, the ung@hordaland study, surveyed 10,220 adolescents aged 16-18 years (54% girls) about sleep and depression. The sleep assessment included measures of the basic sleep parameters for weekdays and weekends. Depression was defined as scoring above the 90th percentile on the total score of Short Moods and Feelings Questionnaire (SMFQ). There was a large overlap between insomnia and depression in both genders and across depressive symptoms. Depressed adolescents exhibited significantly shorter sleep duration and time in bed as well as significantly longer sleep onset latency (SOL) and wake after sleep onset (WASO). Adolescents with insomnia had a 4- to 5-fold increased odds of depression compared to good sleepers. There was also a significant interaction between insomnia, sleep duration and depression, with a more than eightfold increase in odds of depression for those who met criteria for insomnia and who slept <6 h. These associations held for both genders, but were stronger in boys. To the best of our knowledge, this is the first population-based study to investigate sleep and insomnia in relation to depression among adolescents. The findings call for increased awareness of sleep problems and depression as a major public health issue.
睡眠问题和抑郁在青少年中都很常见,但在该年龄段缺乏明确的大型流行病学研究。本研究旨在探讨青少年(16-18 岁)人群中抑郁与几种睡眠参数(包括失眠)之间的关系,并探讨潜在的性别差异。2012 年在挪威霍达兰郡进行的一项基于人群的 ung@hordaland 研究调查了 10220 名 16-18 岁的青少年(54%为女性)的睡眠和抑郁情况。睡眠评估包括工作日和周末基本睡眠参数的测量。抑郁定义为短情绪和感觉问卷(SMFQ)总分高于第 90 百分位数。在两性和不同抑郁症状中,失眠和抑郁有很大的重叠。抑郁青少年的睡眠时间和卧床时间明显缩短,入睡潜伏期(SOL)和睡眠后觉醒时间(WASO)明显延长。与睡眠良好者相比,失眠青少年患抑郁的几率增加了 4-5 倍。失眠、睡眠时间和抑郁之间也存在显著的相互作用,对于符合失眠标准且睡眠时间<6 小时的人,患抑郁的几率增加了 8 倍以上。这些关联在两性中都存在,但在男孩中更强。据我们所知,这是第一项针对青少年中睡眠和失眠与抑郁关系的基于人群的研究。这些发现呼吁人们更加关注睡眠问题和抑郁,将其作为一个主要的公共卫生问题。