来自毛蕊叶割舌树树叶的新型细胞毒性阿朴替卢卡烷类化合物。
New cytotoxic apotirucallanes from the leaves of Walsura trichostemon.
作者信息
Sichaem Jirapast, Khumkratok Suttira, Siripong Pongpan, Tip-pyang Santi
机构信息
Natural Products Research Unit, Department of Chemistry, Faculty of Science, Chulalongkorn University, Bangkok, 10330, Thailand.
出版信息
J Nat Med. 2014 Apr;68(2):436-41. doi: 10.1007/s11418-013-0808-6. Epub 2013 Dec 1.
PMID:24293387
Abstract
Three new apotirucallanes (1-3) were isolated from the leaves of Walsura trichostemon. Their structures were identified by interpretation of their spectroscopic data as well as comparison with those reported in the literature. In addition, all isolated compounds were evaluated for their cytotoxicity against KB and HeLa cells.
摘要
从毛蕊叶割舌树的叶子中分离出了三种新的阿朴替鲁卡烷类化合物（1-3）。通过对其光谱数据的解析以及与文献报道的数据进行比较，确定了它们的结构。此外，还对所有分离出的化合物进行了针对KB和HeLa细胞的细胞毒性评估。
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