Komabayashi T, Watanabe K, Izawa T, Tsuboi M
Res Commun Chem Pathol Pharmacol. 1986 Aug;53(2):249-52.
The energy metabolites and the composition of rat pancreas treated with trypsin inhibitor (T.I.) were investigated. T.I. treatment significantly induced the hypertrophy of pancreatic acinar cells and the increase in the amylase and sialic acid contents. However, when the pancreas was perfused by control solution or the solution containing acetylcholine (10(-7) M), the 31P-NMR spectra of energy metabolites in the pancreas treated with T.I. were similar to those of normal rats.
研究了用胰蛋白酶抑制剂（T.I.）处理的大鼠胰腺的能量代谢产物和组成。T.I.处理显著诱导了胰腺腺泡细胞肥大以及淀粉酶和唾液酸含量增加。然而，当用对照溶液或含乙酰胆碱（10^(-7) M）的溶液灌注胰腺时，用T.I.处理的胰腺中能量代谢产物的31P-NMR光谱与正常大鼠的相似。
