Ekroth R, Rossi R F, Tsang V, Jackson A P, Thompson R J, Scallan M, Lincoln C
Thorac Cardiovasc Surg. 1986 Aug;34(4):223-5. doi: 10.1055/s-2007-1020416.
Profound hypothermia and circulatory arrest in infants and children undergoing cardiac surgery were followed by abnormally high plasma levels of creatine kinase isoenzyme BB (CK-BB). Differences in the levels of enzymes in the femoral arterial and jugular venous blood indicated that the origin of the additional enzyme was the brain. The extent of the rise in enzyme levels was related to the duration of circulatory arrest. These data suggest that measurements of the CK-BB enzyme in plasma provide quantitative information about cerebral damage during cardiac surgery.
在接受心脏手术的婴幼儿中，深度低温和循环骤停后，血浆肌酸激酶同工酶BB（CK-BB）水平异常升高。股动脉血和颈静脉血中酶水平的差异表明，额外酶的来源是大脑。酶水平升高的程度与循环骤停的持续时间有关。这些数据表明，血浆中CK-BB酶的测量可为心脏手术期间的脑损伤提供定量信息。
