Kantomaa T
Acta Anat (Basel). 1986;126(4):218-22. doi: 10.1159/000146220.
The function of the multipotential mesenchymal cells in the mandibular condyle was studied histochemically and histologically in 27 Long Evans/Turku rats. Sagittal sections from the temporomandibular joint were stained with haematoxylin and eosin, toluidine blue, or van Gieson's stain. A weakly orthochromatically stained fibrous layer was followed in the upper region by a weakly metachromatically stained mesenchymal cell layer. Deep within this was a strongly metachromatically stained layer of immature chondroblasts. The metachromasia of the matrix of these layers disappeared abruptly in an anterior direction and gradually in a posterior direction. The changes in the staining reactions are explained by the fact that mesenchymal cells can differentiate into chondrogenic or osteogenic cells depending on the environmental conditions. A new hypothesis is presented according to which regulation of the direction of condylar growth is achieved by choosing the cells for chondrogenesis more posteriorly or anteriorly from among the mesenchymal cells covering the whole condylar cartilage.
采用组织化学和组织学方法，对27只Long Evans/Turku大鼠下颌髁突中多能间充质细胞的功能进行了研究。颞下颌关节矢状切片用苏木精和伊红、甲苯胺蓝或范吉森染色。在上方区域，一层弱正染的纤维层之后是一层弱异染的间充质细胞层。在此层深处是一层强异染的未成熟成软骨细胞层。这些层基质的异染性在前部突然消失，在后部逐渐消失。染色反应的变化可以解释为间充质细胞可根据环境条件分化为软骨形成细胞或骨形成细胞。提出了一个新的假说，即通过从覆盖整个髁突软骨的间充质细胞中更靠后或靠前选择软骨形成细胞来实现髁突生长方向的调节。
