Aukett M A, Parks Y A, Scott P H, Wharton B A
Arch Dis Child. 1986 Sep;61(9):849-57. doi: 10.1136/adc.61.9.849.
Previous work at this hospital and elsewhere has shown that anaemia in toddlers is common and is associated with psychomotor delay. It seemed unclear, however, whether this association was cause and effect or merely due to the same underprivileged environment. A double blind randomised intervention study was, therefore, performed. After an initial assessment 97 children with anaemia (haemoglobin 8-11 g/dl) aged 17-19 months received either iron and vitamin C or vitamin C only (control group) for two months and were then reassessed. The children who received the iron had an increased rate of weight gain and more of them achieved the expected rate of development. While iron deficiency anaemia is unlikely to be the only factor in the slower development of children living in underprivileged circumstances, it can at least be easily identified and treated. Routine child health surveillance in such areas should include a haemoglobin determination.
该医院及其他地方之前的研究表明,幼儿贫血很常见,且与精神运动发育迟缓有关。然而,这种关联是因果关系还是仅仅由于相同的贫困环境导致,似乎并不明确。因此,进行了一项双盲随机干预研究。在初步评估后,97名年龄在17至19个月、患有贫血(血红蛋白8 - 11 g/dl)的儿童接受了为期两个月的铁和维生素C补充或仅接受维生素C补充(对照组),之后再次进行评估。接受铁补充的儿童体重增加率更高,更多儿童达到了预期的发育速度。虽然缺铁性贫血不太可能是生活在贫困环境中的儿童发育迟缓的唯一因素,但至少它很容易被识别和治疗。在此类地区的常规儿童健康监测应包括血红蛋白测定。