Anik Y, Anik I, Koc K, Inan N, Akansel G, Demirci A
Kocaeli University School of Medicine, Radiology Department; Umuttepe Kocaeli, Turkey -
Neuroradiol J. 2007 Jun 30;20(3):278-81. doi: 10.1177/197140090702000304.
Lhermitte-Duclos disease (LDD) is a rare hamartomatous focal or diffuse enlargement of the cerebellum with unclear etiology. The characteristic magnetic resonance imaging (MRI) appearance consists of a non-enhancing mass in the cerebellar hemisphere with a striated pattern. The slow growing behavior of this benign lesion is characteristic. In a few reports on magnetic resonance spectroscopy (MRS) findings in LDD, a decreased level of N-acetyl aspartate, increased level of lactate and near normal level of choline were described. The information obtained from MRS is useful to confirm the relatively benign hamartomatous nature of the lesion. This paper reports a case of LDD and describes the MRI and MRS findings.
Lhermitte-Duclos病（LDD）是一种罕见的小脑错构瘤，病因不明，可呈局灶性或弥漫性增大。其特征性磁共振成像（MRI）表现为小脑半球内无强化的肿块，呈条纹状。这种良性病变生长缓慢是其特点。在少数关于LDD磁共振波谱（MRS）结果的报告中，描述了N-乙酰天门冬氨酸水平降低、乳酸水平升高和胆碱水平接近正常。从MRS获得的信息有助于确认病变相对良性的错构瘤性质。本文报告一例LDD病例，并描述其MRI和MRS表现。
