Department of Neurosurgery, Xiangya Hospital, Central South University, Changsha 410008.
Grade of 2015 in Oral Medicine, Medical College of Jinzhou Medical University, Jinzhou Liaoning 121001, China.
Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2021 Feb 28;46(2):195-199. doi: 10.11817/j.issn.1672-7347.2021.190574.
Lhermitte-Duclos disease (LDD) is a type of rare brain tumor located in posterior fossa. A patient with LDD located in the left cerebellum and vermis was admitted by the Department of Neurosurgery, Xiangya Hospital, Central South University. MRI scan showed slightly heterogeneous enhancement at the region close to vermis. The patient underwent partial resection on August 11, 2016 without postoperative chemoradiotherapy. The progress free survival was 11 months and the overall survival was 17 months. What the case reveals is that the partial resection is not beneficial to these patients with LDD as the residual lesion probably recurs in a short term after operation. The pathogenesis, diagnosis and treatment of LDD are explored and summarized in combination with relevant literature.
Lhermitte-Duclos 病（LDD）是一种位于后颅窝的罕见脑肿瘤。中南大学湘雅医院神经外科收治了一名位于左小脑和蚓部的 LDD 患者。MRI 扫描显示蚓部附近区域呈轻度异质性增强。该患者于 2016 年 8 月 11 日接受了部分切除术，术后未进行放化疗。无进展生存期为 11 个月，总生存期为 17 个月。该病例揭示了部分切除术对 LDD 患者无益，因为残余病变在术后短期内可能会复发。结合相关文献，探讨并总结了 LDD 的发病机制、诊断和治疗。
