Institute of Biotechnology and Bioengineering, University of Minho, Campus Gualtar, 4710-057 Braga, Portugal; Leicester School of Pharmacy, Faculty of Health and Life Sciences, De Montfort University, The Gateway, Leicester LE1 9BH, UK; Centre for Textile Science and Technology (2C2T), University of Minho, Campus Azurém, 4800-058 Guimarães, Portugal.
Carbohydr Polym. 2014 Jan 30;101:121-35. doi: 10.1016/j.carbpol.2013.08.078. Epub 2013 Sep 1.
Plants possess a wide range of molecules capable of improve healing: fibre, vitamins, phytosterols, and further sulphur-containing compounds, carotenoids, organic acid anions and polyphenolics. However, they require an adequate level of protection from the environmental conditions to prevent losing their structural integrity and bioactivity. Cyclodextrins are cyclic oligosaccharides arising from the degradation of starch, which can be a viable option as encapsulation technique. Cyclodextrins are inexpensive, friendly to humans, and also capable of improving the biological, chemical and physical properties of bioactive molecules. Therefore, the aim of this review is to highlight the use of cyclodextrins as encapsulating agents for bioactive plant molecules in the pharmaceutical field.
植物拥有广泛的分子,能够改善愈合:纤维、维生素、植物固醇,以及更多含硫化合物、类胡萝卜素、有机酸阴离子和多酚。然而,它们需要足够的保护水平来防止其结构完整性和生物活性丧失。环糊精是淀粉降解产生的环状低聚糖,可以作为一种可行的包封技术。环糊精价格低廉,对人类友好,并且能够改善生物活性分子的生物、化学和物理性质。因此,本综述的目的是强调环糊精作为药用领域中生物活性植物分子的包封剂的使用。