Saedi Babak, Razmpa Ebrahim, Ghalandarabadi Masoomeh, Ghadimi Hamidreza, Saghafi Farnaz, Naseri Mahshid
Department of otorhinolaryngology, Tehran University of Medical Sciences, Tehran, Iran.
Iran J Otorhinolaryngol. 2012 Summer;24(68):113-8.
As one of the most common cancers among head and neck malignancies, cancer of the oral cavity probably has some variations in countries with a high prevalence of esophageal cancer.
Patients with oral cavity cancer who were treated at two tertiary referral centers from January 1999 to January 2009 were included in this study. In addition to demographic data, information regarding personal and family history of head and neck cancer, use of dentures, presence of immune deficiency, consumption of alcohol, and incidence of cigarette smoking was collected. Additionally, a history of opium usage was obtained from the participants in this study. Moreover, an appropriately matched control group was selected for comparisons between the risk factors.
A total of 557 patients were entered into this study over a 10-year period, of whom 219 (39.3%) were female and the remaining 338 (60.7%) were male. The tongue was the most common site of cancer and 9% of the patients had a history of opium abuse, but more than half of the patients did not have any recognized risk factors. The incidence and stage of cancer had a significant relationship with cigarette smoking (P= 0.013).
Tongue cancer in non-smokers is the predominant pattern of oral cavity cancer in Iran.
口腔癌是头颈部恶性肿瘤中最常见的癌症之一，在食管癌高发国家可能存在一些差异。
本研究纳入了1999年1月至2009年1月在两个三级转诊中心接受治疗的口腔癌患者。除人口统计学数据外，还收集了有关头颈癌个人和家族史、假牙使用情况、免疫缺陷状况、饮酒情况以及吸烟发生率的信息。此外，本研究还从参与者那里获取了鸦片使用史。此外，选择了一个匹配得当的对照组以比较危险因素。
在10年期间，共有557名患者进入本研究，其中219名（39.3%）为女性，其余338名（60.7%）为男性。舌部是最常见的癌症发生部位，9%的患者有鸦片滥用史，但超过一半的患者没有任何公认的危险因素。癌症的发生率和分期与吸烟有显著关系（P = 0.013）。
在伊朗，非吸烟者的舌癌是口腔癌的主要类型。
