a Monash-Epworth Rehabilitation Research Centre , Epworth Hospital , Richmond , VIC , Australia.
J Clin Exp Neuropsychol. 2014;36(1):1-14. doi: 10.1080/13803395.2013.863832. Epub 2013 Dec 4.
This study examined the association between cognitive impairment and anxiety disorders following traumatic brain injury (TBI). Sixty-six participants recruited from a rehabilitation hospital completed the Structured Clinical Interview for the DSM-IV (Diagnostic and Statistical Manual of Mental Disorders-Fourth Edition) and cognitive tests at one year post injury. Prevalence of anxiety disorder was 27.3%. Logistic regression analyses revealed that the attention/working memory, information processing, and executive functions models were significantly associated with anxiety disorder. The memory model was not significant. Processing speed emerged as the strongest model associated with anxiety disorder. The role of cognitive impairment in the etiology of anxiety disorders after TBI is discussed, and treatment implications are explored.
本研究探讨了创伤性脑损伤(TBI)后认知障碍与焦虑障碍之间的关系。66 名参与者从康复医院招募,在损伤后一年完成了 DSM-IV 结构临床访谈(精神障碍诊断和统计手册第四版)和认知测试。焦虑障碍的患病率为 27.3%。逻辑回归分析显示,注意力/工作记忆、信息处理和执行功能模型与焦虑障碍显著相关。记忆模型不显著。处理速度是与焦虑障碍最相关的最强模型。讨论了认知障碍在 TBI 后焦虑障碍发病机制中的作用,并探讨了治疗意义。