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越南旋毛虫病的隐性负担:暴发后流行病学研究。

The hidden burden of trichinellosis in Vietnam: a postoutbreak epidemiological study.

机构信息

Parasitology Section, National Centre for Veterinary Diagnosis, 11/78 Giai Phong, Phuong Mai, Dong Da, Hanoi, Vietnam ; Laboratory of Parasitology, Faculty of Veterinary Medicine, Ghent University, 133 Salisburylaan, 9820 Merelbeke, Belgium.

出版信息

Biomed Res Int. 2013;2013:149890. doi: 10.1155/2013/149890. Epub 2013 Nov 7.

Abstract

A cross-sectional study was conducted in Muong Lat town (Thanh Hoa province, North Vietnam), following the confirmed diagnosis of trichinellosis in six patients from that town who had eaten hunted wild boar meat during the Vietnamese lunar year celebration. All inhabitants who declared to have eaten undercooked or raw wild boar meat at the celebration and showed at least one clinical symptom compatible with trichinellosis were included in the study and blood sampled. Anti-Trichinella IgG were determined by ELISA and Western Blot. Seropositive persons were given appropriate albendazole treatment and were followed up. A total of 100 inhabitants met the inclusion criteria. Among these, 30 (30%) had antibodies to Trichinella. Serologically confirmed cases had fever (90.0%), myalgia (86.7%), facial oedema (63.3%), diarrhoea (53.3%), and pain of the masseter muscles (43.3%). Eosinophilia was detected in 83.3% of these individuals. Clinical symptoms resolved in all patients during albendazole treatment. The results suggest that only a proportion of the trichinellosis cases had sought health care during the outbreak. There is a need to implement surveillance and better diagnosis for trichinellosis and to set up educational programs to prevent infection in North Vietnam.

摘要

一项横断面研究在 Muong Lat 镇(越南北部清化省)进行,此前该镇有 6 名患者被确诊患有旋毛虫病,这些患者在越南农历新年庆祝活动中食用了猎捕的野猪肉。所有在庆祝活动中宣称食用了未煮熟或生的野猪肉并出现至少一种与旋毛虫病相符的临床症状的居民均被纳入研究并采集了血液样本。采用 ELISA 和 Western blot 法检测抗旋毛虫 IgG。对血清阳性者给予适当的阿苯达唑治疗并进行随访。共有 100 名居民符合纳入标准。其中,30 人(30%)对旋毛虫具有抗体。血清学确诊病例有发热(90.0%)、肌痛(86.7%)、面部水肿(63.3%)、腹泻(53.3%)和咀嚼肌疼痛(43.3%)。这些人中 83.3%的人嗜酸性粒细胞增多。在阿苯达唑治疗期间,所有患者的临床症状均得到缓解。结果表明,在疫情爆发期间,只有一部分旋毛虫病病例寻求了医疗保健。有必要在越南北部实施旋毛虫病监测和更好的诊断,并制定教育计划以预防感染。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bba7/3838854/e25858ba890f/BMRI2013-149890.001.jpg

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