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[大疱性类天疱疮:一种老年人中应知晓的皮肤疾病]

[Bullous pemphigoid: a cutaneous disorder to be known in aging persons].

作者信息

Perivier Samuel, Trellu Laurence Toutous

机构信息

Service de gériatrie, HUG, 1211 Genève 14.

出版信息

Rev Med Suisse. 2013 Nov 6;9(405):2049-53.

Abstract

Bullous pemphigoid is a rare autoimmune muco-cutaneous disorder involving particularly aged adults. Its incidence may be underestimated. Recent studies show the various clinical presentations that may delay diagnosis up to several years in absence of typical bullous presentation. Diagnosis such as skin adverse event or infection should be quickly eliminated and the autoimmunity confirmed with skin and blood immunology and pathology analysis. Any chronic pruritis or persisting blister in old people should lead to the diagnosis procedures of a bullous pemphigoid.

摘要

大疱性类天疱疮是一种罕见的自身免疫性黏膜皮肤疾病,尤其多见于老年人。其发病率可能被低估。最近的研究表明,在没有典型水疱表现的情况下,其各种临床表现可能会导致诊断延迟数年。应迅速排除诸如皮肤不良事件或感染等诊断,并通过皮肤和血液免疫学及病理学分析来确认自身免疫性。老年人出现任何慢性瘙痒或持续水疱都应进行大疱性类天疱疮的诊断程序。

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